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A kind of pharmaceutical composition for treating diabetes

A composition and diabetes technology, applied in the field of pharmacy, can solve problems such as adverse reactions, and achieve the effect of excellent hypoglycemic effect, easy to carry and take, and good safety in taking

Inactive Publication Date: 2021-01-29
ANHUI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a life-long disease that requires long-term medication. The injection method of insulin often brings a lot of inconvenience to patients. Oral hypoglycemic drugs are mostly chemical drugs, and long-term use can also cause a series of adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A pharmaceutical composition for treating diabetes is made from the following raw materials in parts by weight:

[0034] Paulownia Fruit Extract 85; Chromium Nicotinate 40;

[0035] Turmeric Root Extract 30; Berberine Hydrochloride 100;

[0036] Green Coffee Bean Extract 60.

[0037] The preparation method is as follows:

[0038] (1) Remove impurities from the original medicinal material of Paulownia fruit, wash, dry and crush, add 10 times the volume concentration of 1.5% acetic acid aqueous solution, soak for 1 hour and decoct for 0.5 hour, filter the medicinal solution, and use the filtrate for later use in the same extracting the dregs repeatedly once under the conditions, filtering, combining the filtrates, concentrating under reduced pressure to a small volume, and then spray-drying to obtain the Paulownia fruit extract;

[0039] (2) After washing, drying and pulverizing the turmeric roots, add 10 times the amount of 40% ethanol, soak for 2 hours and then reflu...

Embodiment 2

[0043] A pharmaceutical composition for treating diabetes is made from the following raw materials in parts by weight:

[0044] Paulownia Fruit Extract 84; Chromium Nicotinate 37;

[0045] Turmeric Root Extract 28; Berberine Hydrochloride 98;

[0046] Green Coffee Bean Extract 56.

[0047] The preparation method is the same as in Example 1.

Embodiment 3

[0049] A pharmaceutical composition for treating diabetes is made from the following raw materials in parts by weight:

[0050] Paulownia Fruit Extract 88; Chromium Nicotinate 42;

[0051] Turmeric Root Extract 32; Berberine Hydrochloride 105;

[0052] Green Coffee Bean Extract64.

[0053] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention relates to the field of pharmacy, in particular to a pharmaceutical composition for treating diabetes. The pharmaceutical composition of the invention is composed of paulownia fruit extract, chromium nicotinate, turmeric root extract, berberine hydrochloride and green coffee bean extract. It is confirmed by pharmacological and toxicological experiments that the pharmaceutical composition of the present invention has a very ideal hypoglycemic effect in a mouse model of diabetes, and has good safety in administration. In addition, the pharmaceutical composition of the present invention can be made into various oral dosage forms, which are convenient to carry and take.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a pharmaceutical composition for treating diabetes. Background technique [0002] Diabetes is a syndrome of metabolic abnormalities caused by the interaction of genetic and environmental factors. Defects in insulin secretion, insulin action, or both lead to metabolic disorders of carbohydrates, proteins, fats, water, and electrolytes, with long-term hyperglycemia as the main common clinical feature. Long-term diabetes can cause chronic complications of multiple system organs, leading to dysfunction and failure, and become the main cause of disability and death. [0003] Since the etiology and pathogenesis of diabetes are not yet fully understood, there is still a lack of effective etiological treatments. Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a lifelong disease that requires long-term medication. The...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P3/10A23L33/105A23L33/10A61K31/4375A61K31/455
CPCA23V2002/00A61K31/4375A61K33/24A61K36/74A61K36/80A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A23L33/10A23L33/105A61K2300/00A23V2200/328A23V2250/21
Inventor 李长润
Owner ANHUI UNIVERSITY
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