Method for producing medical polyvinyl alcohol sponge

A technology of polyvinyl alcohol sponge and polyvinyl alcohol, applied in the medical field, can solve the problems of hard silicone tube end, poor drainage effect, easy hardening, etc., and achieve satisfactory mechanical properties of the material, good biocompatibility, and no particles The effect of shedding

Inactive Publication Date: 2018-04-13
阿不力克木 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Cigarette drainage" has a certain therapeutic effect on surgical lacuna wounds, but has the following defects: a. Gauze rolls, silicone tubes, etc. are drained through the siphon principle, and the drainage effect is poor, local drainage is uneven, and wound exudates are obtained. Without timely drainage, it will seriously affect the recovery of the wound surface; b. The gauze roll and one end of the silicone tube are exposed to the air, which is prone to retrograde infection; c. The gauze roll is made of cellulose material with strong toughness, and the silicone tube is made of silica gel. The silicone is easy to harden after a long time, and the end of the silicone tube is hard, which leads to poor compliance of the two materials, and long-term use will cause strong pain in the affected area

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The preparation method of the medical polyvinyl alcohol sponge of the present embodiment comprises the steps:

[0019] A: Add polyvinyl alcohol into water at room temperature under stirring, disperse evenly, then heat up to 90°C, and stir to prevent agglomeration and affect the dissolution rate; finally, completely dissolve polyvinyl alcohol in water to obtain a polyvinyl alcohol aqueous solution ;

[0020] B: Add a crosslinking agent and a catalyst to the obtained polyvinyl alcohol aqueous solution, and stir for 10 to 40 minutes until the polyvinyl alcohol aqueous solution is mixed with the added crosslinking agent and catalyst;

[0021] C: Pour the solution evenly stirred in step B into a mold, and place it at 50-75°C for 10-24 hours to keep it warm for shaping; In the pool or in the oven to keep the temperature constant, easy to demould and facilitate the post-processing of medical polyvinyl alcohol sponge;

[0022] D: After demoulding and cleaning, a rectangular m...

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Abstract

The purpose of the invention is to provide a method for producing medical polyvinyl alcohol sponge, having the advantages of low cost and simple process. The method for producing the medical polyvinylalcohol sponge comprises the following steps: 1, completely dissolving polyvinyl alcohol in water at 80-100 DEG C to obtain an aqueous solution of polyvinyl alcohol; 2, adding a cross-linking agent and a catalyst to the aqueous solution of polyvinyl alcohol, and uniformly stirring the obtained solution; 3, pouring the uniformly stirred solution obtained in step 2 into a die, and carrying out heatinsulation at 50-75 DEG C for 10-24 h to realize setting; and 3, carrying out demolding and cleaning to obtain the medical polyvinyl alcohol sponge. The medical polyvinyl alcohol sponge produced through the method can be used in vacuum drainage carriers, has the advantages of good biocompatibility, porous and easy drainage, strong soft compliance, no shedding particles, clinically needed mechanical performances, small irritation on wounds, unobvious foreign body sensation, and facilitation of the rehabilitation of patients.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a preparation method of medical polyvinyl alcohol sponge. Background technique [0002] Surgical lacunar wounds are mainly manifested as sinus tracts and fistulas, and their main hazards are as follows: a. Because surgical lacunar wounds are not easy to heal and recurrent, chronic diseases often occur, resulting in a long course of disease for patients, and some patients even persist for 5-6 years. If it does not heal, it brings a heavy burden to the family and the society, and greatly occupies public medical resources; b. Pus and exudate flow out from the affected area of ​​patients with surgical lacuna wounds, accompanied by stench, which seriously affects the quality of life of patients and destroys The physical and mental health of the patient is life-threatening in severe cases; c. Surgical lacuna wounds are caused by infections at the wounds or surgical incisio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08J9/00C08J3/24A61L26/00
CPCA61L26/0014A61L26/0085C08J3/24C08J9/0023C08J2329/04C08L29/04
Inventor 阿不力克木梁志林王健阿吉木
Owner 阿不力克木
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