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Application of triphenol compounds and antibacterial material

A technology of phenolic compounds and antibacterial materials, which is applied in the field of antibacterial agents, can solve the problems of no triphenol compounds, etc., and achieve good antibacterial effect and good inhibitory effect

Active Publication Date: 2018-04-17
JIANGHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there is no record and report of triphenol compounds as antibacterial agents

Method used

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  • Application of triphenol compounds and antibacterial material
  • Application of triphenol compounds and antibacterial material
  • Application of triphenol compounds and antibacterial material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The triphenol compound A and the triphenol compound B were respectively subjected to minimum inhibitory concentration (Minimum InhibitionConcentration, MIC) test experiments, and the specific experimental steps were as follows:

[0022] (1) Inoculate a little bacterium from the flat plate in an Erlenmeyer flask equipped with LB medium (Luria-Bertani medium), and culture it on a shaking table at 37°C for 8-10h; wherein, the test strains include: Gram-positive bacteria and Gram-positive bacteria Lambert-negative bacteria; the formula of LB medium is as follows: tryptone (Tryptone) 10g / L, yeast extract (Yeast extract) 5g / L, sodium oxide (NaCl) 10g / L.

[0023] (2) In the morning of the second day, the bacterial solution was drawn from the Erlenmeyer flask and transferred to the Erlenmeyer flask containing 20ml of LB medium at a volume ratio of 1%, and continued to be cultured in a shaker at 37°C for 2h to 3h until OD600 (OD600 means the absorbance value of the bacterial liq...

Embodiment 2

[0028] Triphenol compound A and triphenol compound B were respectively subjected to minimum inhibitory concentration (Minimum InhibitionConcentration, MIC) test experiments, and the specific experimental steps were as follows:

[0029] (1) Inoculate a little bacteria from the plate in an Erlenmeyer flask equipped with LB medium (Luria-Bertani medium), and culture it on a shaker at 37°C for 10-12h; wherein, the bacteria include: Gram-positive bacteria and Gram Negative bacteria; the formula of LB medium is as follows: tryptone (Tryptone) 10g / L, yeast extract (Yeast extract) 5g / L, sodium oxide (NaCl) 10g / L.

[0030] (2) In the morning of the second day, the bacterial solution was drawn from the Erlenmeyer flask and transferred to the Erlenmeyer flask containing 20ml of LB medium at a volume ratio of 1%, and continued to be cultured in a shaker at 37°C for 4h to 5h until OD600 (OD600 means the absorbance value of the bacterial liquid at 600nm wavelength) is 0.6-0.8, and the speci...

Embodiment 3

[0035] The triphenol compound A and the triphenol compound B were respectively subjected to minimum inhibitory concentration (Minimum InhibitionConcentration, MIC) test experiments, and the specific experimental steps were as follows:

[0036] (1) Inoculate a little bacterium from the flat plate in an Erlenmeyer flask equipped with LB medium (Luria-Bertani medium), and culture it on a shaking table at 37°C for 12~14h; wherein, the test strains include: Gram-positive bacteria and Gram-positive bacteria Lambert-negative bacteria; the formula of LB medium is as follows: tryptone (Tryptone) 10g / L, yeast extract (Yeast extract) 5g / L, sodium oxide (NaCl) 10g / L.

[0037] (2) In the morning of the second day, draw the bacterial solution from the Erlenmeyer flask and transfer it to the Erlenmeyer flask containing 20ml of LB medium at a volume ratio of 1%, and continue to cultivate in a shaker at 37°C for 6h to 7h until OD600 (OD600 means the absorbance value of the bacterial liquid at ...

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Abstract

The invention discloses application of triphenol compounds and an antibacterial material and belongs to the technical field of antibacterial agents. The triphenol compound A and the triphenol compoundB may serve as antibacterial agents. The triphenol compounds A and B provided herein can significantly inhibit growth of gram-positive bacteria and have good antibacterial effect.

Description

technical field [0001] The invention belongs to the technical field of antibacterial agents, and in particular relates to the application of a triphenol compound and an antibacterial material. Background technique [0002] Antibacterial materials are a new class of functional materials with bactericidal and antibacterial properties, and are widely used. Its core component is antibacterial agent, and antibacterial agent is mainly divided into two categories: inorganic antibacterial agent and organic antibacterial agent, by adding a small amount of antibacterial agent to ordinary materials, it has antibacterial properties. Although inorganic antibacterial materials have high activity, they are prone to discoloration and high cost; and organic antibacterial agents are not suitable for adding to plastics and resins due to their poor heat resistance. These defects limit the scope of application of antibacterial materials. [0003] Triphenol compounds can be widely used in indust...

Claims

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Application Information

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IPC IPC(8): A01N31/08A01P1/00
CPCA01N31/08
Inventor 郭锐曹慧明李准洁王玲梁勇
Owner JIANGHAN UNIVERSITY
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