Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of scar removal drug for external application

A medicament, a technology for removing scars, applied in the directions of pharmaceutical formulations, preparations for skin care, medical preparations with non-active ingredients, etc. Generation, promotion of fibroblast and collagen fiber production, free radical scavenging effect

Inactive Publication Date: 2018-05-29
常州市天宁区鑫发织造有限公司
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a preparation method of an externally applied medicament for scar removal in view of the current scar melanin deposition, the effective ingredients of scar removal products are easy to lose, and the scar removal effect is not ideal.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of scar removal drug for external application

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] A preparation method for externally applied medicament for removing scars, comprising the steps of:

[0027] (1) Add aloe, angelica dahurica, Chinese yam and baicalin into distilled water according to the mass ratio of 7:5:4:5:100, soak for 3~5h, mash, filter, take the filtrate A, and pour the filtrate into the filtrate according to the mass ratio of 1:10 Add ethanol solution to A, shake for 2~3 days, filter, take the filtrate B, and rotary evaporate to obtain the ethanol-free mixture, concentrate to obtain the concentrated mixture, add distilled water to dissolve the concentrated mixture at a mass ratio of 1:20, and vacuum dry to obtain the mixed Chinese medicine powder, spare;

[0028] (2) Add the pretreated extraction materials to Tris-HCl buffer at a mass ratio of 1:4, homogenize in an ice bath at -2°C, extract at 4~5°C for 24~36h, 4°C, 10000r / min Centrifuge for 30 min, take the supernatant, and get the extract of Chiziai earthworm, and set aside;

[0029] (3) Tak...

example 1

[0032] Add aloe, angelica dahurica, Chinese yam and baicalin into distilled water at a mass ratio of 7:5:4:5:100, soak for 3 hours, mash, filter, take filtrate A, add ethanol solution to filtrate A at a mass ratio of 1:10 , vibrate for 2 days, filter, take the filtrate B, and rotary evaporate to obtain the ethanol-free mixture, concentrate to obtain the concentrated mixture, add distilled water to dissolve the concentrated mixture at a mass ratio of 1:20, and vacuum dry to obtain mixed Chinese medicine powder. Apply the mixed Chinese medicine powder on the hands of the subjects twice a day to test the melanin-inhibiting and antioxidant properties of the mixed Chinese medicine powder. Skin melanin content MI value: Based on the principle of spectral absorption (RGB), the content of melanin in the skin is determined by measuring the amount of reflection of light of a specific wavelength on human skin. The measurement range of the instrument is 0-999, the higher the measurement v...

example 2

[0037] Pretreatment of bee pollen: Purchase unbroken bee pollen, pass through an 80-mesh sieve to remove other bee pollen and impurities, dry at 70°C, and grind to obtain pretreated bee pollen.

[0038] Eisenia chinensis: purchased from an earthworm farm.

[0039] Pretreatment of extracted raw materials: After the live worms are washed with deionized water, the filter paper absorbs the surface moisture of the live worms, and the concentration is 0.01mol / L Tris at a pH of 7.0 in an ice bath at -4°C -In HCl buffer solution, use a sterile scalpel to cut off the 1 / 3 of the worm near the tail, mark it, take the first 2 / 3 of the worm and put it back in the soil to grow freely for 2 days, then take the worm and cut it off The newly grown body parts in the body must be pre-processed to extract raw materials.

[0040] Pretreatment of Eucheuma: Take Eucheuma, wash repeatedly with tap water twice to remove sediment and debris on its surface, then repeatedly rinse once with distilled wat...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of a scar removal drug for external application, and belongs to the field of cosmetics. The preparation method comprises the following steps: using mixed traditional Chinese medicine powder, an eisenia fetida extracting solution, an antimicrobial peptide solution and bee pollen as raw materials of the scar removal drug for external application, and taking natural high polymer material chitosan as a component for compatibility of medicines supplemented with two film forming matters such as gelatin and sodium carboxymethylcellulose. Effective ingredients of the drug are adhered to the surfaces of the scars, the active ingredients of the drug are unlikely to lose, and the scar removal drug for external application which is antibacterial, is resistant to melanogenesis and promotes new cytopoiesis around the scars and healing of the scars. The drug solves the problems that scar melanin is sedimentated at present, the effective ingredients of a scar removal product is easy to lose and the scar removal effect is non-ideal.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a preparation method of an external application medicament for removing scars. Background technique [0002] Scar refers to the general term for the appearance, morphology and histopathological changes of normal skin tissue caused by various traumas. It is a normal and inevitable physiological reaction in the natural healing process of the wound or wound surface after human trauma, and it is also an inevitable result of the wound healing process. The essence of scar is a kind of abnormal and unsound tissue that does not have normal skin tissue structure and physiological function, and loses normal tissue vitality. Scars not only destroy the body surface, but also hinder the physiological functions of related tissues or organs, and even cause deformities. What "scars" bring to patients is huge physical pain and mental pain, especially the scars left over from burns, scalds, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61K47/42A61K47/38A61K47/36A61P17/02A61P31/02A61P17/00A61P17/18A61K8/9794A61K8/9789A61K8/97A61K8/98A61K8/64A61K8/73A61K8/365A61K8/65A61Q19/00A61Q17/00A61Q19/02A61Q19/08A61K36/896A61K36/8945A61K35/62A61K35/64
CPCA61K36/8945A61K36/896A61K38/02A61K47/36A61K47/38A61K47/42A61Q17/005A61Q19/00A61Q19/02A61Q19/08A61K8/365A61K8/645A61K8/65A61K8/731A61K8/736A61K8/97A61K8/987A61K9/0014A61K35/62A61K35/63A61K36/00A61K36/232A61K36/539A61K36/886A61K2236/51A61K2236/53A61K2800/5922A61K2800/782A61K2236/331A61K2300/00
Inventor 郭剑郑薇程依
Owner 常州市天宁区鑫发织造有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com