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Oral liquid with placenta stem cell factors and method for preparing oral liquid
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A technology of placental stem cells and oral liquid, which is applied in the fields of extracellular fluid diseases, medical preparations containing active ingredients, blood diseases, etc., and can solve problems such as high content of miscellaneous proteins, low degree of industrialization, and complicated purification process of stem cell factors
Inactive Publication Date: 2018-06-12
内蒙古元本生物医药科技有限公司
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Abstract
Description
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Problems solved by technology
Although genetically engineered stem cell factors have been published, there are still the following problems in becoming a drug: first, the degree of industrialization is low and the cost is too high; Adverse reactions; thirdly, the preparation, formula, stability, and pharmacokinetics of the finished medicine still need to be further discussed
However, dietary foods (including oral liquids) that supplement stem cell factors through diet have not been marketed in China
Method used
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Examples
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Effect test
Embodiment 1
[0034] The present invention is achieved through the following technical solutions.
[0036] Weigh 5 kg of goat placenta raw material, wash it with water first, then add deionized water to wash it in proportion (W / W, 1:3), separate the placental amniotic membrane and chorion, and cut them into 1.5×1.5cm pieces shape. The shredded amnion and chorion were added in deionized water in proportion (W / W, 1:7) and hemolyzed at 2-8°C for 24 hours respectively, during which they were stirred once every 6 hours. After hemolysis, wash with deionized water 3 times by weight.
[0039] Animal health inspection, that is, pre-slaughter inspection. In order to obtain healthy sheep placenta, the health status of the donor flock should be accurately assessed. The method is to evaluate the health of the donor sheep according to the local "herd health...
Embodiment 2
[0080] When the amnion and chorion were statically analyzed and concentrated, they were left to stand for 60 days; when homogeneously lysed, the mass ratio of the substance to water for injection was 1:7, and the rest were the same as in Example 1.
Embodiment 3
[0082] When the amnion and chorion were statically analyzed and concentrated, they were left to stand for 150 days respectively; when homogeneously lysed, the mass ratio of the substance to water for injection was 1:9, and the rest were the same as in Example 1.
[0085] After radiotherapy and chemotherapy, hematopoietic function did not recover, and 41 cases had symptoms of anemia, including 25 males and 16 females.
[0086] 2. Treatment method:
[0087] When in use, take orally 3 times a day, 10-20 ml each time. Take orally according to the course of treatment. 3 months and 1 course of treatment.
[0089] Cure: the symptoms disappear, the function is complete or basically returned to normal, and the curative effect is consolidated after half a year of observation.
[0090] Significant effect: most of the original symptoms are el...
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Abstract
The invention relates to oral liquid with placentastem cell factors and a method for preparing the oral liquid. The oral liquid with the placentastem cell factors is selectively made of animal placentas. Amniotic membranes and chorion are reserved after the animal placentas are pretreated, reserved substances are purified and disinfected, acid treatment and static concentration are carried out on the reserved substances, the reserved substances are mixed with one another to obtain ultimate materials, and oral tissue lysate with the placentastem cell factors can be prepared by means of lysisand taste correction emulsification after the materials are homogenized, can be used as food for special dietary use, and particularly can be used as formula food for special medical use. The oral liquid and the method have the advantages that nutritional requirements of special people can be met by the oral liquid, the problems in the aspects of the safety, the effectiveness and the stability ofproducts, dosage forms, formulas and the like can be solved by the aid of the method, and the oral liquid and the method are suitable for industrial production.
Description
technical field [0001] The invention relates to the field of food for special dietary use, in particular to the field of formula food for special medical use, in particular to an oral liquid containing placental stem cell factor and a preparation method thereof. Background technique [0002] The placenta is an organ for material exchange between the mammalian mother and the fetus. It is a combination of embryonic and maternal tissues, mainly composed of amniotic membrane, phyllodes chorion and decidua basalis. Placenta contains rich and efficient nutrients. In recent years, with the deepening of research, various stem cells have been extracted and cultured from umbilical cord blood, umbilical cord, placenta and other tissues. Among them, the placenta is known as the "treasure house of stem cells" and is a precious life resource. [0003] Stem cell factor is a kind of cytokine with a wide range of biological activities. In vivo studies have shown that stem cell factor has a ...
Claims
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Application Information
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