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Preparation method of cold capsule

A cold capsule and capsule technology, which is applied in the direction of capsule delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as unsuitable for long-term application, uneven quality of medicines, and influence on curative effect, etc., to achieve The preparation method is simple and easy, and the effect of ensuring stability and quality is guaranteed

Inactive Publication Date: 2018-06-15
赵双龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] (2) Pseudoephedrine: acts on the α-adrenergic receptors of the respiratory mucosa, relieves nasal congestion, has little effect on the α-receptors of the heart and other peripheral blood vessels, relieves nasal congestion, and improves sleep, but it is not suitable for long-term use. 3- 5 days limit
[0006] (3) Antihistamines: The first-generation antihistamines such as chlorpheniramine maleate (chlorpheniramine) are effective in reducing sneezing and rhinorrhea. The elderly with prostatic hyperplasia should be used with caution, non-sedative Antihistamines lack anticholinergic effects and are uncertain
[0008] There are also many traditional Chinese medicines for treating colds. Among them, Antelope Jiaomao Capsules are highly praised by people because of their moderate price and remarkable curative effect. However, the quality of medicines from various manufacturers varies. The extraction rate directly affects the price of the drug, so there is an urgent need for a preparation method that can improve the extraction quality and extraction rate of the volatile oil to ensure the quality of the drug and reduce the price of the drug

Method used

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  • Preparation method of cold capsule
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preparation example Construction

[0044] The invention provides a kind of preparation method of Ganmao capsule, comprises the following steps:

[0045] Step 1, crushing antelope horns with 5-10 parts by weight to 100-150 mesh to obtain antelope horn powder;

[0046] Step 2, pulverizing platycodon grandiflorum with a weight part of 200-280 to 100-150 mesh to obtain platycodon grandiflorum powder;

[0047] Step 3, placing the Nepeta 150-200 parts by weight in an extraction tank to extract the Nepeta volatile oil;

[0048] Step 4, using the water distillation method to extract the volatile oil of Forsythia, placing 300-400 parts by weight of Forsythia in the extraction tank to extract the volatile oil of Forsythia;

[0049]Step 5. Combine the medicinal residues and medicinal liquid produced in steps 3 and 4 with the following raw materials in parts by weight: 300-400 parts by weight of honeysuckle, 150-200 parts by weight of bamboo leaves, 100-200 parts by weight of fermented soybeans, 200-280 parts by weight of...

Embodiment 1

[0076] A preparation method for cold capsules, comprising the following steps:

[0077] Step 1, crushing antelope horns with a weight of 7.5 to 120 mesh to obtain antelope horn powder;

[0078] Step 2, pulverizing platycodon grandiflorum with 240 parts by weight to 120 mesh to obtain platycodon grandiflorum powder;

[0079] Step 3, placing 180 parts by weight of Schizonepeta in an extraction tank to extract Schizonepeta volatile oil;

[0080] Step 4, using water distillation to extract the volatile oil of Forsythia, placing 360 parts by weight of Forsythia in the extraction tank to extract the volatile oil of Forsythia;

[0081] Step 5. Mix the dregs and medicinal liquid produced in steps 3 and 4 with the following raw materials in parts by weight: 360 parts by weight of honeysuckle, 180 parts by weight of bamboo leaves, 150 parts by tempeh, 240 parts by burdock seeds and 150 parts by weight of licorice, and add 4 times the volume of distilled water After mixing and decoctin...

Embodiment 2

[0087] A preparation method for cold capsules, comprising the following steps:

[0088] Step 1, crushing antelope horns with a weight of 7.5 to 120 mesh to obtain antelope horn powder;

[0089] Step 2, pulverizing platycodon grandiflorum with 240 parts by weight to 120 mesh to obtain platycodon grandiflorum powder;

[0090] Step 3, placing the Schizonepeta 180 parts by weight in the extraction tank as claimed in claim 6 to extract the Schizonepeta volatile oil;

[0091] Step 4, using water distillation to extract the volatile oil of Forsythia, placing 360 parts by weight of Forsythia in the extraction tank as claimed in claim 6 to extract the volatile oil of Forsythia;

[0092] Step 5. Mix the dregs and medicinal liquid produced in steps 3 and 4 with the following raw materials in parts by weight: 360 parts by weight of honeysuckle, 180 parts by weight of bamboo leaves, 150 parts by tempeh, 240 parts by burdock seeds and 150 parts by weight of licorice, and add 4 times the vo...

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Abstract

The invention discloses a preparation method of a cold capsule. The cold capsule is prepared by mixing and decocting for twice honeysuckle, lophatherum gracile, fermented soybean, burdock, liquorice,and leftovers of schizonepeta and fructus forsythia, wherein the leftovers of schizonepeta and fructus forsythia are obtained after volatile oil is extracted; concentrating an obtained filtrate into apaste, mixing with a platycodon grandiflorus powder to prepare a particle, mixing the volatile oil of the schizonepeta, the volatile oil of the fructus forsythia and peppermint oil to prepare an inclusion compound, and finally evenly mixing the particle, the inclusion compound and an antelope horn powder, and packaging in a capsule shell to prepare the cold capsule. The preparation method is simple, the volatile oil of the schizonepeta and the volatile oil of the fructus forsythia are stable and not lost easily, so that the performance of the medicine is effectively guaranteed.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a preparation method of cold capsules. Background technique [0002] Cold is divided into narrow sense and broad sense. In the narrow sense, it refers to the common cold, which is a mild viral infection of the upper respiratory tract (nose and throat); in the broad sense, it also includes influenza, which is generally more serious than the common cold and has additional symptoms. Including fever, chills and muscle soreness, systemic symptoms are more obvious, and the symptoms after a cold are unbearable, and the course of the disease is generally about 7 days, which seriously affects people's normal study and life. [0003] At present, there are many medicines for treating colds in Western medicine, but the general curative effect is not significant, and there are many side effects, such as: [0004] (1) Ipratropium Bromide (Ipratropium Bromide) Spray: Place...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K9/48A61K47/69A61P11/00A61P31/16C11B9/02A61K35/32A61K31/045
CPCA61K9/48A61K31/045A61K35/32A61K36/28A61K36/346A61K36/355A61K36/48A61K36/484A61K36/534A61K36/538A61K36/634A61K36/899A61K2236/331A61K2236/39A61K2236/51C11B9/022C11B9/025C11B9/027A61K2300/00
Inventor 张晓宇
Owner 赵双龙