Complexion brightening cosmetic composition and application thereof
A cosmetic composition and a technology for brightening skin tone, applied in the field of cosmetic compositions for brightening skin tone, can solve problems such as thickening of the stratum corneum, dullness, loss of transparency of the skin, etc., and achieve the effect of brightening the skin tone
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Embodiment 1
[0038] Example 1: Transdermal absorption rate of brewer's yeast lysate filtrate in different systems
[0039] In this example, the transdermal absorption rate of brewer's yeast lysate filtrate in aqueous system and non-aqueous system was tested and compared. The specific test formula is shown in Table 2 below.
[0040] Table 2
[0041]
[0042] Test method: The "reconstructed human epidermis" obtained by culturing "human keratinocytes" is used, and there is a maintenance medium on the lower side of the reconstructed human epidermis. According to the above test formula, the brewer's yeast lysate filtrate was prepared into a 0.5% solution with Bambusa Vulgaris water or water respectively, and 32ul / cm 2 The above solutions were applied to the epidermis layer of the skin model, and the detection was started after contacting for 8 hours. Make 3 parallels for each point. Before the test, the skin tissue was washed with phosphate buffer solution, the tissue was homogenized, an...
Embodiment 2
[0046] Example 2: Toner composition of the present invention vs. contrast toner composition
[0047] The formulations of each toner composition are shown in Table 4 below.
[0048] Table 4
[0049]
[0050] The above toner composition is prepared as follows:
[0051] 1. Mix and heat methylparaben and phenoxyethanol to 70°C, stir and dissolve evenly.
[0052] 2. Mix hydroxyethyl cellulose, brewer's yeast lysate filtrate and butanediol evenly.
[0053] 3. Heat the bamboo (BAMBUSA VULGARIS) water (or water) to 70°C, add citric acid, glycerin, and methyl gluceth-20 in sequence, stir evenly, and then add the mixture obtained in steps 1 and 2.
[0054] 4. Cool down to 40°C, add arginine to adjust pH, and discharge.
[0055] Efficacy Evaluation of the Toner Composition Gained in Example 2—Tyrosinase Activity Inhibition Rate Test
[0056] Using 0.2 mol / L phosphate buffer solution (PBS) with pH=6.8 as a solvent, solutions of the toner composition obtained in Example 2 with a co...
Embodiment 3
[0063] Embodiment 3: a kind of stock solution that brightens complexion
[0064] The original solution for brightening complexion of the present invention vs. the original solution for brightening complexion
[0065] The formulations of each brightening solution are shown in Table 6-9 below:
[0066] Table 6
[0067]
[0068] Table 7
[0069]
[0070] Table 8
[0071]
[0072] Table 9
[0073]
[0074] Efficacy evaluation of the stock solution for brightening skin tone obtained in Example 3—the change rate of skin brightness. The skin-lightening stock solution obtained above was used in experiments to test the effect of skin-lightening.
[0075] The more luminous the skin, the more effective the toner composition will be. The change of skin brightness is reflected in the change law of the L value of the experimental area over time during the test period.
[0076] Skin brightness difference (ΔT) = L value at each time point after using the product (Tn) - L valu...
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