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Coating composition and related use thereof

A composition and coating technology, which is applied in the directions of non-active components of polymer compounds, medical preparations of non-active components, inorganic non-active components, etc., can solve the problems that do not involve the composition ratio and performance, etc. , good viscoelasticity, good stability effect

Inactive Publication Date: 2018-09-18
鲍引健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent WO0051569 discloses methods and devices for coating various dosage forms of drugs, which discloses coating compositions, but does not involve the description of the specific composition and performance of such compositions

Method used

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  • Coating composition and related use thereof
  • Coating composition and related use thereof
  • Coating composition and related use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]

[0032] The preparation method of the coating composition: mix maltitol, sodium alginate and an appropriate amount of water at 50° C. until the material dissolves, record the weight of the added water, and obtain material A. Mix gelatin and 3 times the amount of water at 70°C and stir evenly to obtain material B. Add material A to material B, stir evenly, then slowly raise the temperature to 90°C, maintain this temperature, and perform a depressurization operation on the system to evaporate the excess water in it, calculate the water to be removed according to the weight of the feed, and the composition. gross weight. When the moisture in the system reaches the required amount, the operation is stopped and the obtained composition is naturally cooled.

Embodiment 2

[0034]

[0035]

[0036] The preparation and operation method of the composition is the same as in Example 1, wherein the mixing temperature of the material part A is 55°C, and the temperature for evaporating water is 95°C.

Embodiment 3

[0038]

[0039] The preparation and operation method of the composition is the same as in Example 1, wherein the mixing temperature of part A of material is 45°C, the mixing temperature of part B of material is 65°C, and the water in material B is 2.5 times the weight of gelatin. The temperature for evaporating water is 93°C.

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Abstract

The present invention relates to a coating composition and a related use thereof, and the composition has good stability, can be used as a coating material for a solid dosage form drug, and improves the swallowing performance of the drug while improving the mouthfeel of the drug. At the same time, a raw material of the composition is easy to obtain, a preparation method is simple, and the storageis easy.

Description

Technical field: [0001] This application relates to a composition, which can be used to coat different drugs and related preparations, such as tablets, pills, etc., and the obtained drugs have different advantages for individual specific needs, which can facilitate swallowing and prevent drug deterioration , prolong the shelf life of drugs, etc. Background technique: [0002] Coating the active ingredient with medical use can be made into different dosage forms of the drug, and different coating compositions or components can be selected according to different purposes to achieve different purposes, such as: improving the storage time of the active ingredient, including The drug behind the coat has a better release rate in the body, and promotes the dissolution and absorption of the active ingredient of the drug. Patent WO0051569 discloses methods and devices for coating various dosage forms of medicines, and discloses coating compositions, but does not describe the specifi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/26A61K47/36A61K47/42A61K47/44A61K47/12A61K47/04A61K47/02
CPCA61K47/02A61K47/12A61K47/26A61K47/36A61K47/42A61K47/44
Inventor 鲍引健
Owner 鲍引健