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Nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver and preparation method thereof

A technology of hydrogel and traditional Chinese medicine lipid, which is applied in the field of nanometer traditional Chinese medicine liposome hydrogel preparation and preparation, can solve the problems of patients being intolerable, protracted, and slow to take effect, and achieve constant drug dosage, obvious effect, and easy operation. easy effect

Inactive Publication Date: 2018-09-25
山东今古医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine treatment is slow to take effect, and the course of treatment is long. If Chinese medicine is taken orally, it will cause gastrointestinal stimulation and liver first-pass effect. If other treatments are often protracted, it is difficult for patients to tolerate

Method used

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  • Nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver and preparation method thereof

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Effect test

Embodiment 1

[0059] A method for preparing a nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver, comprising:

[0060] Step 1: Preparation of Nano Chinese Medicine Liquid

[0061] (11) The raw materials will be weighed according to the following weight ratio: 10 parts of Hawthorn, 36 parts of Alisma, 8 parts of Polygonum multiflorum, 10 parts of Bupleurum, 20 parts of Chuanxiong, 40 parts of Angelica, 8 parts of lotus leaf, 15 parts of Codonopsis, 36 parts of Ginseng , 10 parts of Ganoderma lucidum, 10 parts of Acanthopanax, 45 parts of Achyranthes bidentata, 12 parts of leaking reed, 36 parts of soybean, and 15 parts of Scallion. Put the above-mentioned traditional Chinese medicine into an ultra-fine jet mill, set the feeding speed to 50g / min, and the crushing particle size to 20-50nm, and finely pulverize the traditional Chinese medicine;

[0062] (12) Put the above-mentioned ultra-finely pulverized Chinese medicine powder in a tradi...

Embodiment 2

[0071] A method for preparing a nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver, comprising:

[0072] Step 1: Preparation of Nano Chinese Medicine Liquid

[0073] (11) The raw materials will be weighed according to the following weight ratio: 30 parts of Hawthorn, 12 parts of Alisma, 20 parts of Polygonum multiflorum, 20 parts of Bupleurum, 30 parts of Chuanxiong, 12 parts of Angelica, 20 parts of lotus leaf, 30 parts of Codonopsis, 12 parts of Ginseng , 30 parts of Ganoderma lucidum, 30 parts of Acanthopanax, 15 parts of Achyranthes bidentata, 30 parts of leaking reed, 10 parts of soybean, and 36 parts of Scallion. Put the above-mentioned traditional Chinese medicine into an ultra-fine jet mill, set the feeding speed to 50g / min, adjust the crushing particle size to 20-50nm, and finely pulverize the traditional Chinese medicine;

[0074] (12) Put the above-mentioned ultra-finely pulverized Chinese medicine powder in a ...

Embodiment 3

[0083] A method for preparing a nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver, comprising:

[0084] Step 1: Preparation of Nano Chinese Medicine Liquid

[0085] (11) The raw materials will be weighed according to the following weight ratio: 15 parts of Hawthorn, 30 parts of Alisma, 10 parts of Polygonum multiflorum, 20 parts of Bupleurum, 20 parts of Chuanxiong, 30 parts of Angelica, 15 parts of lotus leaf, 15 parts of Codonopsis, 20 parts of Ginseng , 20 parts of Ganoderma lucidum, 25 parts of Acanthopanax, 40 parts of Achyranthes bidentata, 20 parts of leaking reed, 10 parts of soybean, and 30 parts of Scallion. Put the above-mentioned traditional Chinese medicine into an ultra-fine jet mill, set the feeding speed to 50g / min, adjust the crushing particle size to 20-50nm, and finely pulverize the traditional Chinese medicine;

[0086] (12) Put the above-mentioned ultrafinely pulverized Chinese medicine powder in a C...

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Abstract

The invention discloses a nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver and a preparation method thereof, and belongs to the field of traditional Chinese medicine for treating obesity diseases. The nanometer traditional Chinese medicine liposome hydrogel preparation for treating obesity and fatty liver is prepared from a traditional Chinese medicine recipe, a lipidosome recipe and an aquogel recipe, wherein the traditional Chinese medicine recipe is prepared from the following ingredients: fructus crataegi, rhizoma alismatis, radix polygoni multiflori preparata, radix bupleuri, rhizoma chuanxiong, radix angelicae sinensis, lotus leaves, radix codonopsis, radix ginseng, glossy ganoderma, radix acanthopanax, radix achyranthis bidentatae, uniflower swisscentaury roots, soybean and bulbus allii macrostemi; the lipidosome recipe is prepared from the following ingredients: lecithin and cholesterol; the aquogel recipe is prepared from the following ingredients including sodium alginate, glycerol and deionized water. The nanometer traditional Chinese medicine liposome hydrogel preparation has the advantages that the effect takingis fast; the treatment course is short; no wound exists; no pain exists; the side effect is small, and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treating obesity, and specifically provides a nanometer traditional Chinese medicine liposome hydrogel preparation and a preparation method for treating obesity and fatty liver. Background technique [0002] Obesity is a complex, multifactorial, and characterized by increased adipose tissue, a common endocrine and metabolic disease caused by specific factors such as genetics and environment. It is divided into: simple obesity, accounting for about 95.00% of obese people , dietary regulation and energy metabolism disorders, excessive body fat accumulation and excessive body weight are the main causes of its disease; secondary obesity, accounting for about 5% of obese people, is often one of the clinical manifestations of diseases such as hypothalamus and pituitary tumors one. Obesity is closely related to type 2 diabetes, fatty liver, cardiovascular and cerebrovascular diseases, res...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K9/127A61K9/06A61K47/36A61P3/04A61P1/16
CPCA61K9/0014A61K9/06A61K9/127A61K36/074A61K36/21A61K36/232A61K36/233A61K36/236A61K36/254A61K36/258A61K36/28A61K36/344A61K36/48A61K36/62A61K36/704A61K36/734A61K36/884A61K36/8962A61K47/36A61K2236/331A61P1/16A61P3/04A61K2300/00
Inventor 高鹏李斐李立
Owner 山东今古医疗科技有限公司