Carbetocin injection
A carbetocin and injection technology, which is applied in the field of medicine, can solve the problems of uterus increasing the suffocation in childbirth and the limited effect, and achieve the effects of shortening the farrowing interval, shortening the labor process, and improving the effect of uterine contraction.
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Embodiment 1
[0026] The carbetocin injection of this embodiment includes carbetocin, sodium alginate, vitamin D2, benzyl alcohol and sodium acetate, and the composition of every 2mL carbetocin injection is: carbetocin The content of sodium alginate is 70 μg, the content of sodium alginate is 6 mg, the content of vitamin D2 is 3 mg, the content of benzyl alcohol is 1.9 mg and the content of sodium acetate is 27 mg. Acetic acid is used as a pH regulator to adjust the pH to 4.0, and the balance is water for injection.
[0027] Weigh 90% of the prescribed amount of water for injection into the batching tank, add the prescribed amount of sodium alginate, vitamin D2, benzyl alcohol and sodium acetate, dissolve and mix well, adjust the pH value to 4.0 with acetic acid, and then add carbetocin , stirred at 80rpm for 40min at 50°C, dissolved and mixed evenly, cooled to 25°C, added water for injection to make up to volume, after constant volume, passed secondary filtration through 0.45μm and 0.22μm p...
Embodiment 2
[0029] The carbetocin injection of this embodiment includes carbetocin, pectin (65% esterification degree, molecular weight of 150,000), vitamin D2, benzyl alcohol and sodium acetate, and every 2mL of carbetocin The composition of the injection is: the content of carbetocin is 70 μg, the content of pectin (65% esterification, molecular weight is 150,000) is 6 mg, the content of vitamin D2 is 3 mg, the content of benzyl alcohol is 1.9 mg and sodium acetate The content is 27 mg, using acetic acid as the pH regulator, using acetic acid as the pH regulator to adjust the pH to 4.0, and the balance being water for injection.
[0030]Weigh 90% of the prescribed amount of water for injection into the batching tank, add the prescribed amount of pectin, vitamin D2, benzyl alcohol and sodium acetate, dissolve and mix, adjust the pH value to 4.0 with acetic acid, then add carbetocin, Stir at 80rpm for 40min at 50°C, dissolve and mix well, then cool to 25°C and add water for injection to m...
Embodiment 3
[0032] The carbetocin injection of this embodiment includes carbetocin, pectin (40% esterification degree, molecular weight of 150,000), vitamin D2, benzyl alcohol and sodium acetate, and every 2mL of carbetocin The composition of the injection is as follows: the content of carbetocin is 70 μg, the degree of pectin esterification is 40%, the molecular weight is 150,000), the content is 6 mg, the content of vitamin D2 is 3 mg, the content of benzyl alcohol is 1.9 mg and the content of sodium acetate 27mg, use acetic acid as the pH regulator, use acetic acid as the pH regulator, adjust the pH to 4.0, and the balance is water for injection.
[0033] Weigh 90% of the prescribed amount of water for injection into the batching tank, add the prescribed amount of pectin, vitamin D2, benzyl alcohol and sodium acetate, dissolve and mix, adjust the pH value to 4.0 with acetic acid, then add carbetocin, Stir at 80rpm for 40min at 50°C, dissolve and mix well, then cool to 25°C and add wate...
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