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Antibacterial urinary catheter and preparation method thereof

A urinary catheter and antibacterial agent technology, which is applied in the field of antibacterial urinary catheter and its preparation, can solve problems affecting patients' medication, performance of urinary catheter, and troubles in doctor's diagnosis, and achieve prolonged indwelling time, low cost, and antibacterial The effect of small doses

Active Publication Date: 2018-10-02
青岛杰圣博生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Urinary catheter is an important medical device, mainly used in patients with general anesthesia and dysuria, and plays an irreplaceable role in urine drainage and lowering of bladder pressure. However, according to the research data of the US CDC, the catheter 10-30% of indwelling urinary catheters will cause urinary tract infection, and 1-4% of patients can cause blood infection, which can even lead to death in severe cases. Therefore, more and more attention has been paid to the prevention of urinary catheter infection
[0003] The current antibacterial catheters are mainly divided into two categories: one is directly mixed with antibacterial agents, such as silver-based antibacterial agents or other spectrum antibiotics in the catheter material, and the other is coated with antibacterial agents on the surface, such as in catheter materials. The surface of the urinary catheter is coated with compound antibiotics or spectrum antibiotics, but the antibacterial materials mixed in may also affect other performances of the urinary catheter, and the addition of antibiotics will affect the patient’s medication and cause trouble for the doctor’s normal diagnosis; especially the first In one method, the amount of antimicrobial agent incorporated is large, the production cost is high, and the antibacterial agent incorporated can only play an antibacterial effect if it penetrates into the surface part

Method used

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  • Antibacterial urinary catheter and preparation method thereof
  • Antibacterial urinary catheter and preparation method thereof
  • Antibacterial urinary catheter and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0046] A preparation method for an antibacterial urinary catheter, comprising the following steps:

[0047] (1) Soak the drainage tube body in methanol for 1 to 2 hours and then dry to obtain a pretreated drainage tube body. After pretreatment, the surface gap of the drainage tube body becomes larger, which helps tyrosine to replace titanine zinc into the gap;

[0048](2) In parts by weight, 0.5-1 part of phthalocyanine photosensitive antibacterial agent is dissolved in 100 parts of methanol, and then the pretreated drainage tube body obtained in step (1) is put into it, soaked for 5-10 minutes, dried, and then Coating a curing agent on the outermost layer, such as polyvinylpyrrolidone PVP, and drying; through the coating of PVP, not only the coating of phthalocyanine photosensitive antibacterial agent can be cured, but also the lubricity of the catheter surface can be improved;

[0049] (4) Fill the air cavity with side-light optical fibers, generally 3 to 5, and then connect...

Embodiment 1

[0051] Such as figure 1 As shown, an antibacterial urinary catheter includes a drainage tube 1, a transparent outer tube 2 is arranged on the periphery of the drainage tube 1, an inflatable cavity 3 is formed between the inner wall of the transparent outer tube 2 and the outer wall of the drainage tube 1, and a balloon is arranged on the transparent outer tube 2 4. The inflatable cavity 3 communicates with the balloon 4 and the inflatable nozzle 5. A plurality of side-light optical fibers 6 are arranged on the inner circumference of the inflatable cavity 3. The side-light optical fibers 6 are connected to the optical fiber light source 7. The outer wall of the transparent outer tube 2 is surrounded by phthalocyanine. A photosensitive antibacterial agent layer 8, and a curing agent layer 9 is arranged on the periphery of the phthalocyanine photosensitive antibacterial agent layer 8.

Embodiment 2

[0053] The structure of the antibacterial catheter is as in Example 1, the difference is that the phthalocyanine photosensitive antibacterial agent layer 8 is tyrosine substituted zinc cyanine, and its structural formula is

[0054]

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Abstract

The invention discloses an antibacterial urinary catheter. The antibacterial urinary catheter comprises a drainage pipe, a transparent outer pipe is arranged on the periphery of the drainage pipe, andan air inflation cavity is formed between the inner wall of the transparent outer pipe and the outer wall of the drainage pipe; a balloon is arranged on the transparent outer pipe, the inflation cavity is communicated with the balloon and an inflation nozzle, and a plurality of side light optical fibers are arranged on the inner circumference of the inflation cavity and connected with an opticalfiber light source device; a phthalocyanine photosensitive antibacterial agent layer is arranged on the periphery of the outer wall of the transparent outer pipe, and a curing agent layer is arrangedon the periphery of the phthalocyanine photosensitive antibacterial agent layer. According to the antibacterial urinary catheter, a urinary catheter body serves as an inner cavity, and an outer cavityand the balloon are connected to fix the urinary catheter; the phthalocyanine photosensitive antibacterial agent layer is arranged on the periphery of the outer wall of the transparent outer pipe, and the layer can generate free-state or singlet oxygen under the irradiation of the side light optical fibers connected with the optical fiber light source device, so that a good antibacterial effect is achieved, the urinary tract infection probability of the urinary catheter is greatly reduced, and the safety of the urethral catheter is improved.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to an antibacterial urinary catheter and a preparation method thereof. Background technique [0002] Urinary catheter is an important medical device, mainly used in patients with general anesthesia and dysuria, and plays an irreplaceable role in urine drainage and lowering of bladder pressure. However, according to the research data of the US CDC, the catheter 10-30% of indwelling urinary catheters will cause urinary tract infection, and 1-4% of patients can cause blood infection, and even death in severe cases. Therefore, more and more attention has been paid to the prevention of urinary catheter infection. [0003] The current antibacterial catheters are mainly divided into two categories: one is directly mixed with antibacterial agents, such as silver-based antibacterial agents or other spectrum antibiotics in the catheter material, and the other is coated with antibacter...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10C07F3/06A61L29/16A61L29/08A61L29/14
CPCA61L29/08A61L29/085A61L29/14A61L29/16A61L2300/216A61L2300/404A61L2300/606A61L2400/10A61M25/0017A61M25/1011A61M25/1027A61M2025/1013A61M2025/1031A61M2205/0205C07F3/06C08L39/06
Inventor 仲学雷金桥赵运超
Owner 青岛杰圣博生物科技有限公司
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