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Identity relationship verification method, device, equipment and storage medium

A technology of identity relationship and identification method, which is applied in the field of devices, equipment and storage media, and identification method of identity relationship, which can solve the problems of limited number of STRs, influence of identification results, and susceptibility to mutation, and achieve the effect of improving effectiveness and reliability

Active Publication Date: 2020-04-10
GUANGZHOU KINGMED DIAGNOSTICS CENT +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A single STR is more prone to mutations than SNPs, and due to the limited number of available STRs, even a single mutation will have a greater impact on the final identification results

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  • Identity relationship verification method, device, equipment and storage medium
  • Identity relationship verification method, device, equipment and storage medium
  • Identity relationship verification method, device, equipment and storage medium

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Embodiment Construction

[0035] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the associated drawings. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, these embodiments are provided to make the understanding of the disclosure of the present invention more thorough and comprehensive.

[0036] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field of the invention. The terms used herein in the description of the present invention are for the purpose of describing specific embodiments only, and are not intended to limit the present invention. As used herein, the term "and / or" includes any and all combinations of one or more of ...

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Abstract

The invention relates to an identity relationship identification method, device, equipment and storage medium capable of improving the effectiveness and reliability of identification results. In the identity relationship identification method, when identifying the identity relationship, the multiple target SNP sites are retrieved one by one in the mutation sites of the sample mutation information to obtain the mutation and sequencing information of the genotype including each target SNP site, and from Select the target SNP site and its mutation and sequencing information that meet the preset requirements from multiple target SNP sites to obtain identification information, and finally compare the genotypes of the corresponding target SNP sites in the identification information of different samples. identification of the identity relationship. Since the mutation rate of SNP mutations in other directions is extremely low, even if a single target SNP is mutated, the impact on the final result is limited. Therefore, the identification of identity relationship through SNP can be significantly improved compared with the traditional method of using STR detection. Validity and reliability of identification results.

Description

technical field [0001] The invention relates to the technical fields of molecular biology and bioinformatics, in particular to an identity relationship identification method, device, equipment and storage medium. Background technique [0002] At present, methods for identity relationship identification such as individual identification and kinship identification (including paternity identification) are mainly based on STR (short tandem repeat, short tandem repeat sequence) detection. The study found that the number of STRs in the human genome is very small compared to SNP (Single Nucleotide Polymorphism, single nucleotide polymorphism), and there are fewer STRs with high discrimination for individual differentiation, and the frequency of STRs fluctuates greatly in different populations In this case, the remaining usable STRs are very limited. However, a single STR is more likely to mutate than a SNP, and because the number of available STRs is limited, even if only one muta...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16B20/20C12Q1/6888
CPCC12Q1/6888C12Q2600/156G16B30/00
Inventor 刘晶星刘菲菲庞柳赵薇薇于世辉
Owner GUANGZHOU KINGMED DIAGNOSTICS CENT