Repairing gel as well as preparation method and application thereof

Abstract

The invention provides repairing gel as well as a preparation method and application thereof, relating to the technical field of skin care products. The skin care gel is prepared from basic fibroblastgrowth factors bFGF and precursor sol; the mass ratio of the basic fibroblast growth factors bFGF to the precursor sol is (1-2) to 1,000,000. The bFGF can maintain relatively good stability in the precursor sol, and still has relatively good activity when stored for half a year in a normal temperature status through detection, thereby effectively remitting the problem that current bFGF ingredient-contained skin care products are difficult to preserve at normal temperature. Meanwhile, various ingredients in the precursor sol and various ingredients which cooperate with the bFGF in use not onlycan respectively give play to original effects but also can have a synergistic effect simultaneously, the curative effect of the repairing gel is further reinforced, and the repairing gel is obviously superior to current skin care products in remitting symptoms such as dry skin, senility, dark yellow, color spots, acne and allergy.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to a repair gel and its preparation method and application. Background technique [0002] As early as 1940, Hoftman found a substance that could promote the growth of fibroblasts in the extracts of the brain and pituitary gland. In 1974, the substance was isolated and purified, and named as fibroblast growth factor (fibroblast growthfactor, FGF). Then people isolated a highly homologous substance, because it contains more acidic amino acid bases, and its isoelectric point is acidic (5.6), so it was named acidic FGF (aFGF). Acid and heat sensitive, the isoelectric point is alkaline (9.6), it is called basic FGF (bFGF). [0003] Basic fibroblast growth factor bFGF is a mitogenic cationic polypeptide containing 155 amino acids, with a molecular weight of 16-18.5KD. Success in purification by heparin-agarose affinity chromatography followed the high degree of purification ...

AI Technical Summary

Problems solved by technology

Therefore, due to these shortcomings of bFGF in the application field, the price of bFGF-containing skin care products is relatively high. Generally, it is stored in a solid state after freeze-drying, and it needs to be reconstituted when used, which seriously limits its popularization and application.

[0006] Therefore, research and development of a bFGF-containing skin care product that can be preserved at room temperature for a long time, to alleviate the problem that the existing bFGF-containing skin care products are not easy to preserve at room temperature, and then reduce the price of bFGF in the field of skin care applications, It is very necessary and urgent to make it easier to be accepted by the public

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