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Traditional Chinese medicine composition for preventing senile dementia and preparation method of traditional Chinese medicine composition

A technology for senile dementia and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., which can solve problems such as limited treatment effect, lack of alternative drugs, etc.

Inactive Publication Date: 2018-11-06
芜湖耄智生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the types of drugs for the treatment of Alzheimer's disease in clinical practice are quite limited. They are basically a few small molecule chemical drugs. Intervention, the curative effect is mainly limited relief and compensation for symptoms such as memory loss or nerve tissue degeneration, the therapeutic effect is very limited, and a drug is prone to tolerance after a period of use, and there is a lack of alternative drugs

Method used

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preparation example Construction

[0014] The invention provides a preparation method of a traditional Chinese medicine composition for preventing senile dementia, the preparation method comprising:

[0015] (1) Mix Huangshi, Polygonatum, Ginseng, Chuanxiong, Lycium barbarum, Shichangpu, Cistanche and water, then decoct for the first time and decoct for the second time respectively, and obtain the filtrate M after filtering;

[0016] Wherein, the time for the first decoction is 10-30min; the time for the second decoction is 40-50min; the interval between the first decoction and the second decoction is 20-25min;

[0017] (2) Rhubarb, Cordyceps sinensis, kudzu flower, Schisandra chinensis, Poria cocos, dendrobium, eclipta, Panax notoginseng and honeysuckle are mixed and then ground to obtain mixed powder N;

[0018] (3) Heating and melting the tortoise shell glue, and then adding the filtrate M and mixed powder N to obtain a mixture A, which is sterilized and dried to obtain the traditional Chinese medicine compo...

Embodiment 1

[0028] Mix Huangshi, Polygonatum, Ginseng, Chuanxiong, Lycium barbarum, Shichangpu, Cistanche and water, then decoct for the first time and decoct for the second time respectively, and filter to obtain the filtrate M; wherein, the time for the first decoction The time for the second decoction is 40min; the interval between the first decoction and the second decoction is 20min; rhubarb, Cordyceps sinensis, kudzu flower, southern Schisandra, Poria cocos, Dendrobium, Eclipta , Radix Notoginseng and Flos Lonicerae are mixed according to the mass ratio of 1:0.5:0.9 and then ground to obtain a mixed powder N; the tortoise shell gum is heated and melted, and then the filtrate M and the mixed powder N are added to obtain a mixture A, and the mixture A The traditional Chinese medicine composition is obtained after sterilization (conditions for sterilization include temperature of 110° C. for 5 minutes) and drying (conditions for drying include: pressure of -0.07 MPa, temperature of 60° ...

Embodiment 2

[0030] Mix Huangshi, Polygonatum, Ginseng, Chuanxiong, Lycium barbarum, Shichangpu, Cistanche and water, then decoct for the first time and decoct for the second time respectively, and filter to obtain the filtrate M; wherein, the time for the first decoction The time for the second decoction is 50min; the interval between the first decoction and the second decoction is 25min; rhubarb, Cordyceps sinensis, kudzu flower, southern Schisandra, Poria cocos, Dendrobium, Eclipta , Panax notoginseng and Flos Lonicerae are mixed according to the mass ratio of 1:0.7:1.2 and then ground to obtain a mixed powder N; the tortoise shell gum is heated and melted, and then the filtrate M and the mixed powder N are added to obtain a mixture A, and the mixture A The traditional Chinese medicine composition was obtained after sterilization (conditions for sterilization include temperature of 115° C. for 10 minutes) and drying (conditions for drying include: pressure of -0.06 MPa, temperature of 80...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing senile dementia and a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of mixing radix astragali, rhizoma polygonati, ginseng, ligusticum wallichii, lycium barbarum, rhizoma acori graminei, cistanche and water, then respectively decocting for the first time and for the second time, filtering to obtain a filtrate M, mixing rheum officinale, cordyceps sinensis, flos puerariae, kadsura longepedunculata, poria cocos, dendrobe, eclipta alba, pseudo-ginsengand honeysuckle, and grinding to obtain a mixed powder N; heating and melting a tortoise-plastron glue, adding the filtrate M and the mixed powder N, obtaining a mixture A, and sterilizing and dryingthe mixture A to obtain the traditional Chinese medicine composition; the preparation method of the provided traditional Chinese medicine composition is simple, and the raw materials are easy to get;in addition, the treatment effect is good, and no side effect is caused.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing senile dementia and a preparation method thereof. Background technique [0002] Alzheimer's disease (AD) is a neurodegenerative disease with insidious onset and progressive development. Clinically, it is characterized by comprehensive dementia such as memory impairment, aphasia, apraxia, agnosia, impairment of visuospatial skills, executive dysfunction, and personality and behavior changes. The etiology is still unknown. Those with onset before the age of 65 are called Alzheimer's disease; those with onset after the age of 65 are called senile dementia. At present, the types of drugs for the treatment of Alzheimer's disease in clinical practice are quite limited. They are basically a few small molecule chemical drugs. The curative effect of intervention is mainly limited relief and compensation for symptoms s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P25/28A61K35/586
CPCA61K35/586A61K36/068A61K36/076A61K36/236A61K36/258A61K36/28A61K36/355A61K36/481A61K36/488A61K36/57A61K36/64A61K36/708A61K36/79A61K36/815A61K36/888A61K36/8969A61K36/8984A61K2236/331A61K2236/39A61K2236/51A61P25/28A61K2300/00
Inventor 王以科
Owner 芜湖耄智生物科技有限公司
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