SNP loci associated with obesity and/or hypertriglyceridemia in Chinese children and their application

A high triacylglycerol, site technology, applied in the field of biotechnology and medical detection
CN108753945BActive Publication Date: 2022-03-01首都儿科研究所
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
首都儿科研究所
Publication Date
2022-03-01

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Abstract

The invention discloses the application of SNP sites in the preparation of early detection products for Chinese children's obesity and / or hypertriglyceridemia. The SNP sites are rs189326455, specifically chr1:233463936, c.162G>C, p.Glu54Asp . The present invention studies the genetic locus rs189326455 related to obesity as an early biomarker of obesity and hypertriglyceridemia, in order to further study the genetic molecular mechanism of obesity and hypertriglyceridemia, and to explore the early prevention and treatment of obesity and hypertriglyceridemia The drug target provides a new direction.
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Description

technical field

[0001] The present invention relates to the technical fields of biotechnology and medical detection, in particular to SNP sites related to obesity and / or hypertriglyceridemia in Chinese children and their application, the SNP site is rs189326455, specifically chr1:233463936, c. 162G>C, p.Glu54Asp. Background technique

[0002] Obesity is a common nutritional metabolic disease. With the improvement of material living conditions in modern society, changes in diet structure, accelerated pace of life, and factors such as mental stress and lack of exercise, the number of overweight and obese people is increasing day by day . Existing evidence shows that obesity is closely related to hypertension, diabetes, dyslipidemia, and metabolic syndrome, and brings about a high risk of cardiovascular disease. In 2002, WHO listed obesity as one of the global first-level risk factors causing the burden of human disease. Preventing the prevalence of obesity is also one of...

Claims

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