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Anti-tumor drug containing Disporum cantoniense polysaccharide and use method thereof

An anti-tumor drug, the technology of ginseng polysaccharide, applied in the field of medicine, can solve the problem that the anti-tumor effect of ginseng polysaccharide has not been reported, and achieve the effect of inhibiting the growth of malignant tumors and inhibiting the activity of tumor proliferation.

Active Publication Date: 2018-11-30
GUIZHOU EDUCATION UNIV
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Problems solved by technology

[0004] There is no report about the anti-tumor effect of ginseng polysaccharides

Method used

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  • Anti-tumor drug containing Disporum cantoniense polysaccharide and use method thereof
  • Anti-tumor drug containing Disporum cantoniense polysaccharide and use method thereof

Examples

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preparation example Construction

[0023] Wherein: the preparation method of the polysaccharide of ginseng ginseng comprises the following steps:

[0024] (1) Degreasing: reflux degreasing at 50° C. for 3 hours in a Soxhlet extractor with the powdered ginseng and petroleum ether at a material-to-liquid ratio of 1:50 to obtain the powdered ginseng;

[0025] (2) Extraction: add distilled water to the degreased ginseng powder, the ratio of solid to liquid is 1:20-80, extract 1-4 times at 70-100°C, each time for 1-4 hours, and the extraction ends combined water extracts;

[0026] (3) Separation: the water extract is suction-filtered with a Buchner funnel, the filtrate is precipitated with 95% ethanol in a ratio of 1:3.5-4, and left standing for 6-8h; centrifuged at 3000-4000r / min for 15-20min, and the supernatant is removed Solution, distilled water for precipitation to 500ml;

[0027] (4) AB-8 resin was decolorized and purified, concentrated to 1 / 3 of the original volume to obtain crude polysaccharide liquid;

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Abstract

The invention discloses an anti-tumor drug containing a Disporum cantoniense polysaccharide and a use method thereof. The Disporum cantoniense polysaccharide is orally used according to 300 mg / kg / dayand simultaneously, 5-fluorouracil F Mu is applied through intraperitoneal injection according to 25 mg / kg / day. The Disporum cantoniense polysaccharide is applied once every day for continuous 14 days. The anti-tumor drug can inhibit tumor proliferation activity and is safe and non-toxic.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antitumor drug containing polysaccharides of ginseng polysaccharides, and also relates to a method for using the antitumor drugs containing polysaccharides of ginseng polysaccharides. Background technique [0002] Disporμrn Cantoniense (Loμt.) Merr is a plant of the genus Disporμm in the Liliaceae family (Liliaceae). The medicinal parts are roots and rhizomes. It is a traditional medicinal material of the Miao nationality. It is sweet, light, flat in nature, and has the effects of nourishing the lungs and relieving cough, invigorating the spleen and eliminating stagnation. It can be used to treat symptoms such as deficiency cough and asthma, blood in phlegm, blood in the intestines, and fullness of food. It is Guizhou Bailing Pharmaceutical Factory. (Anshun) The main medicinal plant in "Ke Su Ting Syrup". Modern pharmacological studies have shown that Athelminth ...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K31/513A61P35/00
CPCA61K31/513A61K31/715A61P35/00A61K2300/00
Inventor 曹剑锋赵云艳龙婷婷徐连巧朱锡健
Owner GUIZHOU EDUCATION UNIV
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