The invention discloses a medicated wine composition which is prepared by soaking the following raw materials in parts by weight in wine: 75-125 parts of dysosma versipellis, 150-250 parts of disporum cantoniense, 150-250 parts of gastrodia elata, 75-125 parts of talinum crassifolium, 150-250 parts of cordyceps sobolifera, 150-250 parts of teasel, 150-250 parts of radix asparagi, 75-125 parts of figs, 75-125 parts of silene baccifera, 150-250 parts of dried ginger, 125-175 parts of radix cynanchi, 150-250 parts of hedyotis uncinella, 150-250 parts of rhizoma curculiginis, 125-250 parts of rhizoma bletillae, 150-250 parts of piper wallichii, 150-250 parts of ganoderma lucidum, 150-250 parts of lycopodium clavatum and 150-250 parts of pink reineckea herb. The medicated wine composition is prepared by soaking the plurality of wild raw materials in the wine in proportion, has the effects of breaking accumulations, activating blood to remove stasis, promoting vital energy circulation to remove toxic materials, naturally secreting saliva or body fluid, dredging the channels, strengthening healthy atmosphere, eliminating evil, tonifying the spleen and stomach, nourishing the lung and the like, can regulate human immunity function and quickly repair visceral system injury, has an effect of targeted repair of empty stomach, and especially has a good mediation effect on hydremic nephritis, sphagitis, rhinitis, bronchitis, acute and chronic enterogastritis, stomach cold, gastro spasm, female uterus cold, male sexual debility, excessively frequent sexual intercourse, internal and external injury and the like.