Traditional Chinese medicine composition for treating sepsis heart failure and preparation method of traditional Chinese medicine composition

A composition and a technology for sepsis are applied in the field of traditional Chinese medicine compositions for the treatment of sepsis heart failure and the field of preparation thereof to achieve the effects of improving the therapeutic effect, reducing myocardial damage and inhibiting cell apoptosis

Inactive Publication Date: 2019-01-04
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it only adapts to and treats general chronic heart failure
[0005] Based on the fact that there is no traditional Chinese medicine formula with good curative effect on heart failure caused by sepsis in the prior art, the applicant has developed a traditional Chinese medicine with good effect on heart failure caused by sepsis through long-term research and experiments Compositions and methods for their preparation

Method used

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  • Traditional Chinese medicine composition for treating sepsis heart failure and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating sepsis heart failure and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating sepsis heart failure and preparation method of traditional Chinese medicine composition

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Embodiment 1

[0026] Recipe: Astragalus: 30 parts, Poria cocos: 20 parts, Salvia: 20 parts, Schisandra: 10 parts; Ophiopogon japonicus 15 parts; The mass ratio of safflower seeds and Fructus Fructus Fructus is 2:1.

[0027] A preparation method of a traditional Chinese medicine composition for the treatment of sepsis heart failure, characterized in that it comprises the following steps:

[0028] (1) The raw materials of the traditional Chinese medicine composition are frozen at a low temperature of -20-40°C and crushed to 150 meshes, then added to the medicine pot, and an aqueous solution is added so that the medicinal materials can be completely soaked in the aqueous solution, and soaked at room temperature for 40 minutes;

[0029] (2) Boil on high heat until the pot boils, then change to low heat and cook for 40 minutes, stirring continuously during this period to prevent the pot from overflowing, and filter out the liquid medicine after boiling;

[0030] (3) Add an aqueous solution to t...

Embodiment 2

[0034] Recipe: Astragalus: 25 parts, Poria cocos: 15 parts, Salvia: 25 parts, Schisandra: 5 parts; Ophiopogon japonicus 20 parts; The mass ratio of safflower seeds and Fructus Fructus Fructus is 1.25:1.

[0035] A preparation method of a traditional Chinese medicine composition for the treatment of sepsis heart failure, characterized in that it comprises the following steps:

[0036] (1) The raw materials of the traditional Chinese medicine composition are frozen at a low temperature of -20-40°C and crushed to 100 meshes, then added to the medicine pot, and an aqueous solution is added so that the medicinal materials can be completely soaked in the aqueous solution, and soaked at room temperature for 60 minutes;

[0037] (2) Boil on high heat until the pot boils, then change to low heat and cook for 20 minutes, stirring continuously during this period to prevent the pot from overflowing, and filter out the liquid medicine after boiling;

[0038] (3) Add an aqueous solution to...

Embodiment 3

[0042] Recipe: Astragalus: 35 parts, Poria cocos: 25 parts, Salvia: 15 parts, Schisandra: 15 parts; Ophiopogon japonicus 10 parts; Tinglizi 20 parts; Citrus aurantium 10 parts; Motherwort 25 parts. 35 parts, wherein the mass ratio of water safflower seeds and Fructus aurantii Fructus is 3.5:1.

[0043]A preparation method of a traditional Chinese medicine composition for the treatment of sepsis heart failure, characterized in that it comprises the following steps:

[0044] (1) The raw materials of the traditional Chinese medicine composition are frozen at a low temperature of -20-40°C and crushed to 200 meshes, then added to the medicine pot, and an aqueous solution is added so that the medicinal materials can be completely soaked in the aqueous solution, and soaked at room temperature for 20 minutes;

[0045] (2) Boil on high heat until the pot boils, then change to low heat and cook for 60 minutes, stirring continuously during this period to prevent the pot from overflowing,...

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Abstract

The invention relates to the field of treatment of sepsis heart failure, in particular to a traditional Chinese medicine composition for treating sepsis heart failure and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition consists of 25-35 parts of radix astragali, 15-25 parts of poria cocos, 15-25 parts of radix salviae miltiorrhizae, 5-15 parts of Chinese magnoliavine fruits, 10-20 parts of radix ophiopogonis, 10-20 parts of tansymustard seeds, 15-25 parts of motherwort and 35-55 parts of princesplume ladysthumb fruits and fructus aurantii, wherein the mass ratio of the added princesplume ladysthumb fruits to the added fructus aurantii is 1.25-3.5 to 1. The lethality caused by sepsis can be reduced, the myocardial damage canbe reduced, and the traditional Chinese medicine composition can resist inflammation, restrain myocardial apoptosis and the like, and has better treatment effects on the sepsis heart failure.

Description

technical field [0001] The invention relates to the field of treating sepsis heart failure, in particular to a traditional Chinese medicine composition for treating sepsis heart failure and a preparation method thereof. Background technique [0002] Sepsis refers to systemic inflammatory response syndrome (SIRS) caused by infection. The incidence of sepsis is high, with more than 18 million cases of severe sepsis worldwide each year. Sepsis is a dangerous condition, with a fatality rate as high as 30% to 50%. About 14,000 people worldwide die from its complications every day. The main complications include heart failure, severe sepsis, septic shock, multiple organ dysfunction syndrome, etc. Central failure is one of the most common causes of death in sepsis. In sepsis, bacterial toxins, cytokines, etc. can cause myocardial insufficiency, myocardial energy metabolism disorder, and myocardial cell apoptosis through different channels, leading to myocardial function inhibitio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P31/04A61P29/00A61P9/04
CPCA61K36/076A61K36/31A61K36/481A61K36/533A61K36/537A61K36/57A61K36/704A61K36/752A61K36/79A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61P9/04A61P29/00A61P31/04A61K2300/00
Inventor 郭玉红徐霄龙刘清泉黄丽娟
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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