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A composition with the function of assisting blood lipid lowering, its preparation method and application

A technology for assisting blood lipid lowering and composition, which is applied in the field of medicine, can solve the problems of low bioavailability and low dissolution rate of ingredients, and achieve the effect of assisting blood lipid lowering function, no toxic side effects, and weight loss

Active Publication Date: 2021-08-17
雷允上药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this comparative patent composition, except that tartary buckwheat is crushed and used as medicine, the other five medicines are all extracted by water, resulting in low dissolution rate of effective index components such as nuciferin, geniposide, and flavonoids, and low bioavailability

Method used

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  • A composition with the function of assisting blood lipid lowering, its preparation method and application
  • A composition with the function of assisting blood lipid lowering, its preparation method and application
  • A composition with the function of assisting blood lipid lowering, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1-pharmaceutical composition granule of the present invention

[0032] ① For the composition with the function of assisting in lowering blood fat, the parts by weight of the raw materials are as follows:

[0033] 25 parts of ginseng, 100 parts of poria cocos, 25 parts of Pu'er tea, 25 parts of gardenia, 60 parts of lotus leaf, and 25 parts of ginkgo leaf.

[0034] ② Preparation steps:

[0035] 1) Take the above Chinese herbal medicines as raw materials.

[0036] 2) Add 3 times the amount of 50% ethanol to extract ginseng, ginkgo leaves, gardenia, and lotus leaves twice, each time for 1.5 hours, and recover the ethanol from the extract under reduced pressure to obtain extract I; add 8 times the amount of Poria cocos and Puer tea Water extraction was performed twice, each time for 1 hour, and the extract was concentrated to obtain Extract II;

[0037] 3) Combine extract I and extract II, pass through a 200-mesh sieve, and concentrate the filtrate to a relati...

Embodiment 2

[0042] Embodiment 2-pharmaceutical composition tablet of the present invention

[0043] ① For the composition with the function of assisting in lowering blood fat, the parts by weight of the raw materials are as follows:

[0044] 38 parts of ginseng, 50 parts of Poria cocos, 38 parts of Puer tea, 40 parts of gardenia, 80 parts of lotus leaf, 40 parts of ginkgo leaf

[0045] ② Preparation steps:

[0046] 1) Take the above Chinese herbal medicines as raw materials.

[0047] 2) Extract ginseng, ginkgo leaves, gardenia, and lotus leaves with 6 times the amount of 20% ethanol for 3 times, each time for 2 hours, and recover the ethanol from the extract under reduced pressure to obtain extract I; add 10 times the amount of Poria cocos and Puer tea Water extraction once, 2 hours each time, the extract was concentrated to obtain Extract II;

[0048] 3) Combine extract I and extract II, pass through a 100-mesh sieve, and concentrate the filtrate to a relative density of 1.25-1.35 (60...

Embodiment 3

[0053] Embodiment 3-pharmaceutical composition oral liquid of the present invention

[0054] ① For the composition with the function of assisting in lowering blood fat, the parts by weight of the raw materials are as follows:

[0055] 30 parts of ginseng, 80 parts of poria cocos, 32 parts of Pu'er tea, 30 parts of gardenia, 70 parts of lotus leaf, and 35 parts of ginkgo leaf.

[0056] ② Preparation steps:

[0057] 1) Take the above Chinese herbal medicines as raw materials.

[0058] 2) Add 3 times the amount of 60% ethanol to extract ginseng, ginkgo leaves, gardenia, and lotus leaves twice, each time for 1 hour, and recover the ethanol from the extract under reduced pressure to obtain Extract I; add 6 times the amount of Poria cocos and Puer tea Water extraction 3 times, 1.5 hours each time, the extract was concentrated to obtain Extract II;

[0059] 3) Combine extract I and extract II, add refined honey and sorbic acid, add water to the specified amount, refrigerate for mo...

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Abstract

The invention discloses a composition with the function of assisting in lowering blood fat and its preparation method and application. Made from 50-100 parts of leaves and 20-50 parts of ginkgo leaves. The composition of the invention has a scientific and reasonable formula, and is selected from common medicinal and edible raw materials. It has been proved by animal functional tests and human experiments that it has a good auxiliary blood lipid-lowering function, is safe and reliable, has no toxic and side effects, and is suitable for long-term use.

Description

technical field [0001] The invention relates to a composition, in particular to a composition with the function of assisting in lowering blood fat and its preparation method and application, belonging to the technical field of medicine. Background technique [0002] With the improvement of modern people's living standards, significant changes have taken place in the diet structure, so that the incidence of hyperlipidemia is increasing year by year. According to the survey, about 10% to 20% of the serum total cholesterol or triglyceride elevation among adults, and even nearly 10% of children have elevated blood lipids. Up to now, the number of people suffering from hyperlipidemia continues to grow with an average of 15 million people per year. Hyperlipidemia is the most serious risk factor for cardiovascular diseases such as coronary heart disease and myocardial infarction. Elevated blood lipids can be said to be "garbage" in blood vessels, especially elevated low-density l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61P3/06A61P1/16A61P3/04A23L33/10A23L33/105
CPCA23V2002/00A61K36/076A61K36/16A61K36/258A61K36/62A61K36/744A61K36/82A61K2236/331A61K2236/333A61K2236/39A23L33/10A23L33/105A61P1/16A61P3/04A61P3/06A61K2300/00A23V2200/3262A23V2200/332A23V2250/208A23V2250/21A23V2250/2122A23V2250/2124A23V2250/214A23V2250/51084A23V2250/51088A23V2250/5118A23V2300/10A23V2300/14A23V2300/50A23V2250/054
Inventor 叶华王恒斌罗年翠刘光曜孙翔李全戴晶晶翟云良辛艳李小冬楼坚伟
Owner 雷允上药业集团有限公司
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