Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat product

A technology for neuraminic acid and meat products, applied in the field of N-glycolylneuraminic acid synthesis and inhibition of N-glycolylneuraminic acid synthesis, can solve the problems of unsatisfactory enzymatic hydrolysis, complex meat-like matrix, retention, etc. Achieve the effect of low cost, obvious effect and reduced synthesis

Inactive Publication Date: 2019-01-18
GUIZHOU UNIV
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Existing technologies for inhibiting the synthesis of N-glycolylneuraminic acid include: mainly including physical methods (boiling, microwave, frying) and adding enzyme preparations to reduce the content of N-glycolylneuraminic acid in meat products, but there are The problems are: (1) There are many deficiencies in reducing the content of Neu5Gc by physical methods, such as boiling, microwave, frying, etc. can only hydrolyze the free Neu5Gc, and most of the bound Neu5Gc remains in the meat products; ( 2) The reduction of Neu5Gc by enzyme preparation can only be processed after slaughter, and due to the complexity of the meat-like matrix, the enzymatic hydrolysis effect is not ideal

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Example 1: A method for effectively inhibiting the synthesis of N-glycolylneuraminic acid in meat products, the method is: the living animals of the meat products to be slaughtered are fed with medicine, and the oral administration is administered by gavage, and the administration is quercetin Quercetin, the amount of quercetin is 200mg / (kg.d), and it is prepared into 1mL solution with 0.5% sodium carboxymethylcellulose solution, and the amount of each gavage is 1mL / d, and the gavage is 30d, and the unit is mg / (kg.d) means how many milligrams per kilogram of body weight of the living animal should be gavaged every day.

Embodiment 2

[0011] Example 2: A method for effectively inhibiting the synthesis of N-glycolylneuraminic acid in meat products, the method is: the living animals of the meat products to be slaughtered are fed with medicine, and the oral administration is administered by gavage, and the administration is quercetin Quercetin, the amount of quercetin is 190mg / (kg.d), and it is prepared into 1mL solution with 0.5% sodium carboxymethylcellulose solution, and the amount of quercetin is 1mL / d each time, and it is administrated for 29 days.

Embodiment 3

[0012] Example 3: A method for effectively inhibiting the synthesis of N-glycolylneuraminic acid in meat products, the method is: the living animals of the meat products to be slaughtered are fed with medicine, and the oral administration is administered by gavage, and the administration is quercetin Quercetin, the amount of quercetin is 210mg / (kg.d), and it is prepared into 1mL solution with 0.5% sodium carboxymethylcellulose solution, and the amount of quercetin is 1mL / d each time, and the intragastric administration is 31d.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat products. The method comprises: administering a live animal to a meat product, and administering the skin as a suede by oral administration. The compound was prepared into a 1 mL solution using a 0.5% sodium carboxymethylcellulose solution, and the amount of perfusion was 1 mL / d, and thestomach was administered for 29 to 31 days. The invention adopts the natural flavonoid quercetin to inhibit the substrate of CMP-Neu5Ac hydroxylase, thereby affecting the activity of CMP-Neu5Ac hydroxylase, thereby reducing the synthesis of Neu5Gc, and performing N-hydroxyacetate nerve from the pre-slaughter living body. The intervention of biochemical synthesis of acid is low in cost and the effect is more obvious.

Description

technical field [0001] The invention relates to a method for effectively inhibiting the synthesis of N-glycolylneuraminic acid in meat products, and belongs to the technical field of inhibiting the synthesis of N-glycolylneuraminic acid. Background technique [0002] Existing technologies for inhibiting the synthesis of N-glycolylneuraminic acid include: mainly including physical methods (boiling, microwave, frying) and adding enzyme preparations to reduce the content of N-glycolylneuraminic acid in meat products, but there are The problems are: (1) There are many deficiencies in reducing the content of Neu5Gc through physical methods, such as boiling, microwave, frying, etc., can only hydrolyze the free Neu5Gc, and most of the bound Neu5Gc remains in the meat products; ( 2) The reduction of Neu5Gc by enzyme preparation can only be done after slaughter, and the effect of enzymatic hydrolysis is not ideal due to the complex matrix of meat samples. Contents of the invention ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/352
CPCA61K31/352
Inventor 朱秋劲周樱子晏印雪常瑞徐阿奇李洪英梁美莲曾雪峰
Owner GUIZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com