Fructus amomi ultrafine powder and preparation method thereof

A technology of superfine powder and Amomum chinensis, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. efficiency, avoid loss, and improve the effect of grinding efficiency

Inactive Publication Date: 2019-02-22
SICHUAN JINSUIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above-mentioned prior art, the present invention provides a method for preparing amomum superfine powder to solve the technical problem of low utilization rate of active ingredients in amomum

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] In order to solve the technical problem of low utilization rate of effective substances in amomum, the present invention proposes a preparation method of amomum superfine powder, comprising the following steps:

[0027] S1: Take the dried amomum with a water content of 8-12%, wrap it with gauze, and break it into fragments with a particle size of about 1cm with a hammer, then put the amomum fragments into liquid nitrogen and soak for 0.5-1h; The soaked fragments are taken out and placed in the air for 3-5 minutes. After the liquid nitrogen is completely volatilized, the Amomum fragments are crushed to 50-60 mesh with a pulverizer to obtain coarse powder of Amomum;

[0028] S2: Put the coarse powder of amomum in a vacuum drying oven, vacuum dry until the water content is lower than 5%, and then uniformly mix the dried coarse powder of amomum with auxiliary materials in a mass ratio of 50 to 100:1 to obtain a mixed powder The adjuvant used in the present invention compris...

Embodiment 1

[0033] A method for preparing amomum superfine powder, comprising the following steps:

[0034] S1: Take 1Kg of dried Hainan sand with a water content of about 10%, break it into fragments with a particle size of 0.5-1cm, then soak the fragments in liquid nitrogen for 0.8h, then remove them and place them in the air for 3min, then Routinely crushed to 60 mesh to obtain Amomum coarse powder;

[0035] S2: Vacuum-dry the coarse powder of Amomum to a water content lower than 5%, then uniformly mix the dried coarse powder of Amomum with 12.5 g of auxiliary materials to obtain a mixed powder; auxiliary materials include 6.25 g of talcum powder, 1.25 g of mannitol, and camphor 1.90g and bornyl acetate 3.1g;

[0036] S3: Put the mixed powder into a superfine pulverizer, and pulverize it for 30 minutes under anhydrous conditions to obtain Amomum superfine powder;

[0037] S4: dry and sterilize the Amomum superfine powder with 300MHz microwave to obtain the final product.

Embodiment 2

[0039] A method for preparing amomum superfine powder, comprising the following steps:

[0040] S1: Take 1Kg of dried Hainan sand with a water content of about 10%, break it into fragments with a particle size of 0.5-1cm, then soak the fragments in liquid nitrogen for 1 hour, then remove them and place them in the air for 5 minutes, and then routinely Pulverize to 50 mesh to get Amomum coarse powder;

[0041] S2: Vacuum-dry the coarse powder of Amomum to a water content lower than 5%, then uniformly mix the dried coarse powder of Amomum with 20 g of auxiliary materials to obtain a mixed powder; auxiliary materials include 10 g of talcum powder, 2 g of mannitol, 3 g of camphor and acetic acid Borneolate 5g;

[0042] S3: Put the mixed powder into a superfine pulverizer, and pulverize it for 20 minutes under anhydrous conditions to obtain Amomum superfine powder;

[0043] S4: dry and sterilize the Amomum superfine powder with 400MHz microwave to obtain the final product.

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Abstract

The invention discloses fructus amomi ultrafine powder and a preparation method thereof. When the ultrafine powder is prepared, the preparation method comprises the steps that firstly, fructus amomi dry products are crushed, soaked in liquid nitrogen for a period of time, and then conventionally ground to 50-60 meshes, and fructus amomi coarse powder is obtained; then the fructus amomi coarse powder and auxiliary materials comprising talcum powder, mannitol, camphor and bornyl acetate are evenly mixed according to the mass ratio being of (50-100) to :1, and thus mixed powder is obtained; and then the mixed powder is put into an ultrafine grinder to be ground for 20-30 minutes under the anhydrous condition, thus the fructus amomi ultrafine powder is obtained, and finally, the fructus amomiultrafine powder is dried and sterilized to obtain a finished product. By adopting the preparation method, fructus amomi, especially amomum longiligulare, can be ground into the evenly-distributed fructus amomi ultrafine powder with the fine grain size, the obtained fructus amomi fine powder has the high contents of volatile oil and the bornyl acetate and can be directly used as medicine, waste ofactive ingredients in the fructus amomi is avoided, and the overall utilization rate of the fructus amomi is increased.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine powder preparation, and in particular relates to superfine amomum powder and a preparation method thereof. Background technique [0002] Amomum is the dry and mature fruit of Zingiberaceae Yangchunsha, Lvkesha or Hainansha. The growth conditions of amomum are harsh, and they need to be grown in high temperature, humid subtropical regions, damp, warm, hot and foggy areas with annual rainfall above 1000mm, such as Yangchun and Gaozhou in Guangdong, and earthquakeproof areas in Guangxi. The yield per mu is about 110 kg, and the annual Amomum production is less. Amomum has the functions of dispelling dampness and appetizing, warming the spleen and stopping diarrhea, regulating qi and preventing miscarriage. It is mainly used for symptoms such as dampness and turbidity in the middle, abdominal distension without hunger, spleen and stomach deficiency and cold, vomiting and diarrhea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61K47/02A61K47/26A61K47/08A61K47/14A61P1/14A61P1/08A61P1/12A61P15/00A61P15/06A61K131/00
CPCA61K36/9064A61K47/02A61K47/08A61K47/14A61K47/26A61K2236/15A61K2236/17A61P1/08A61P1/12A61P1/14A61P15/00A61P15/06
Inventor 韩业详杨文生
Owner SICHUAN JINSUIFANG PHARMA
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