Preparation method and device of autologous platelet-rich plasma for treating pressure injury

A technology for platelet-rich plasma and platelet-poor plasma, applied in separation methods, chemical instruments and methods, liquid separation, etc., can solve the problems of increasing fibroblast proliferation and type I collagen expression, low PRP concentration, and complicated extraction methods, etc. problems, to avoid poor adaptability, short preparation cycle and simple structure

Inactive Publication Date: 2019-02-22
曲靖市第二人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The concentration of platelets in human whole blood is generally 1-3×10 5 /ml, studies have shown that the increase in the concentration of concentrated PRP platelets can effectively improve the proliferation and differentiation capabilities of stem cells, and can also significantly increase the proliferation of fibroblasts and the expression of type I collagen. At present, there are manual methods and equipment preparation methods for the extrac...

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  • Preparation method and device of autologous platelet-rich plasma for treating pressure injury
  • Preparation method and device of autologous platelet-rich plasma for treating pressure injury
  • Preparation method and device of autologous platelet-rich plasma for treating pressure injury

Examples

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Embodiment 1

[0026] The device for preparing autologous platelet-rich plasma for treating pressure injury described in this embodiment includes a centrifuge tube, the centrifuge tube includes an outer tube 1, an inner tube 2 and a sealing cover 3, and the inner wall of the outer tube 1 is closely connected to the outer wall of the inner tube 2. Fitting, the sealing cover 3 is sealed and connected with the upper ends of the outer tube 1 and the inner tube 2, the sealing cover 3 is provided with an injection hole 4 and a ventilation hole 5, and the upper parts of the injection hole 4 and the ventilation hole 5 are screwed with a sealing plug 6, The bottom of the injection hole 4 is provided with a top seal 7 which can be penetrated by a needle, and the inner wall of the outer tube 1 is provided with an integrally connected supporting part 8, and the lower bottom surface of the inner tube 2 is against the supporting part 8, and the bottom of the inner tube 2 A drain pipe 9 is provided, and the...

Embodiment 2

[0042] The device for preparing autologous platelet-rich plasma for treating pressure injury described in this embodiment includes a centrifuge tube, the centrifuge tube includes an outer tube 1, an inner tube 2 and a sealing cover 3, and the inner wall of the outer tube 1 is closely connected to the outer wall of the inner tube 2. Fitting, the sealing cover 3 is sealed and connected with the upper ends of the outer tube 1 and the inner tube 2, the sealing cover 3 is provided with an injection hole 4 and a ventilation hole 5, and the upper parts of the injection hole 4 and the ventilation hole 5 are screwed with a sealing plug 6, The bottom of the injection hole 4 is provided with a top seal 7 which can be penetrated by a needle, and the inner wall of the outer tube 1 is provided with an integrally connected supporting part 8, and the lower bottom surface of the inner tube 2 is against the supporting part 8, and the bottom of the inner tube 2 A drain pipe 9 is provided, and the...

Embodiment 3

[0057] The device for preparing autologous platelet-rich plasma for treating pressure injury described in this embodiment includes a centrifuge tube, the centrifuge tube includes an outer tube 1, an inner tube 2 and a sealing cover 3, and the inner wall of the outer tube 1 is closely connected to the outer wall of the inner tube 2. Fitting, the sealing cover 3 is sealed and connected with the upper ends of the outer tube 1 and the inner tube 2, the sealing cover 3 is provided with an injection hole 4 and a ventilation hole 5, and the upper parts of the injection hole 4 and the ventilation hole 5 are screwed with a sealing plug 6, The bottom of the injection hole 4 is provided with a top seal 7 which can be penetrated by a needle, and the inner wall of the outer tube 1 is provided with an integrally connected supporting part 8, and the lower bottom surface of the inner tube 2 is against the supporting part 8, and the bottom of the inner tube 2 A drain pipe 9 is provided, and the...

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Abstract

The invention discloses a preparation method and device of autologous platelet-rich plasma for treating pressure injury. The preparation method includes the steps: (1) whole blood collection; (2) anticoagulant adding; (3) primary centrifugation; (4) secondary centrifugation; (5) thrice centrifugation; (6) platelet-rich plasma preparation. The preparation device comprises a centrifugal tube, the centrifugal tube comprises an outer tube, an inner tube and a sealing cover, the inner wall of the outer tube is closely fitted with the outer wall of the inner tube, the sealing cover is hermetically connected with the upper ends of the outer tube and the inner tube, a liquid discharging tube is arranged at the bottom of the inner tube, a simple clamp is arranged on the liquid discharging tube, a plurality of liquid pumping holes are formed in the side wall of the inner tube, side wall sealing parts are arranged in the liquid pumping holes, and needle heads can penetrate the side wall sealing parts. The preparation device is simple in structure and convenient to operate, the pollution probability of blood can be reduced in preparation process of the plasma to a great extent, platelets in the prepared plasma are high in concentration, extracting efficiency is high, preparation period is short, feasibility is high, and the preparation device has popularization and use values in clinical practice.

Description

technical field [0001] The invention belongs to the technical field of platelet-rich plasma extraction, and in particular relates to a preparation method and device for autologous platelet-rich plasma for treating pressure injuries. Background technique [0002] Common pressure injuries include pressure sores and decubitus ulcers, which are caused by long-term pressure on local tissues, malnutrition, and blood circulation disorders, resulting in continuous ischemia and hypoxia of local tissues, which eventually lead to local tissue necrosis. Nursing of pressure injuries is difficult , the treatment is more difficult. Autologous platelet-rich plasma, referred to as PRP, is the plasma containing high concentration of platelets obtained by centrifugation of autologous whole blood, and platelets contain a large number of growth factors, such as platelet-derived growth factor, transforming growth factor, insulin-like growth factor, epidermal growth factor These growth factors ca...

Claims

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Application Information

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IPC IPC(8): B01D17/038
CPCB01D17/0217
Inventor 白志瑶母美菊崔关花熊丽巧耿娅萍陈粉英陈萍许志华
Owner 曲靖市第二人民医院
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