The invention discloses a production method of soft sesame-flavor white wine with high ester yield, relating to the technical field of wine making. The production method comprises the following steps:raw material proportioning, raw material treatment, raw material cooking, distiller's yeast stirring, accumulation, cultivation saccharification, fermented grain saccharification and distillation, fermented grain fermentation, pit discharging, wine cooking and storage, blending and storage of finished wine and the like. By soaking grains with hot water and steaming the raw materials in clear soup, the water absorption and gelatinization of red grain starch can be promoted, and the grains can be easily and thoroughly cooked when being cooked, so that the generation of mellow sweet substances is promoted, meanwhile, the raw material flavor and foreign flavor produced in a mixed steaming process can be effectively eliminated, the wine can be relatively clean, and the purity and cleanness ofthe wine can be improved; and compared with sesame-flavor white wine produced by virtue of prior art, the gentleness, softness and comfort are remarkably improved. Compared with the prior art, production method has the advantages that the high-quality wine rate is increased by 25%, the content of ethyl hexanoate is increased by 2-5 times, the richness and mellowness of the sesame-flavor white wineare increased, and a wine body is fine and plump and has obvious perception characters and special individuality.