The invention discloses an efficient disease- and pest-preventing Chenopodium quinoa cultivation method. The method includes the steps of firstly, selecting land on a mountain with the altitude beingabove 2000m; secondly, preparing soil, to be more specific, deeply plowing soil in autumn, and finely breaking and flatly raking the soil, wherein plowing depth is 20-25cm; performing rotary tillage and compression on the soil in next spring; thirdly, applying base fertilizer, to be more specific, evenly applying farm manure to the soil according to the quantity of 500kg/mu; fourthly, ridging andlaying a mulching film, wherein the distance between every two adjacent ridges is 50-60cm; fifthly, performing seed dressing, to be more specific, mixing Chenopodium quinoa with plant ash and millet;sixthly, sowing, to be more specific, sowing the Chenopodium quinoa seed mixture according to the plant distance of 20-25cm, wherein sowing depth is 2-3cm; seventhly, performing field management whichcomprises seedling culture, lateral branch removing, top dressing, weeding and disease and pest control. The method has the advantages that substances such as chemical fertilizer, growth regulators and additives are not used, and pollution to Chenopodium quinoa and environments is reduced.