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A kind of natural composition for treating depression and its preparation method

A composition and technology for depression, applied in the direction of drug combination, medical raw materials derived from molluscs, medical preparations containing active ingredients, etc., can solve the problem of unclear pathogenesis of depression, unsatisfactory clinical effect, and many adverse reactions To achieve the effect of increasing gastrointestinal motility, enhancing activity and promoting survival

Active Publication Date: 2021-06-25
EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the recognition rate of hospitals above prefecture-level cities in China is less than 20%, and only less than 10% of patients have received relevant drug treatment; meanwhile, the onset of depression and possibly accompanying suicide behaviors have begun to appear at a young age (university , and even primary and middle school students) trend
[0003] The specific pathogenesis of depression is still unclear. Many studies have suggested that the main pathological change is the decline in the transmission function of monoamine neurotransmitters in the central nervous system. The concentration of monoamine neurotransmitters, in order to achieve the purpose of treatment, common tricyclic antidepressants, monoamine oxidase inhibitors and neurotransmitter reuptake inhibitors, etc., most of them have a single target, slow onset, and adverse reactions Many, the clinical effect is not ideal

Method used

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  • A kind of natural composition for treating depression and its preparation method
  • A kind of natural composition for treating depression and its preparation method
  • A kind of natural composition for treating depression and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0030] 1. A natural composition for treating depression

[0031] The natural composition comprises the following raw materials in parts by weight: 10 parts of bupleurum, 15 parts of wild jujube seed, 10 parts of curcuma, 10 parts of citrus aurantium, 20 parts of jujube, 25 parts of mother-of-pearl, and 10 parts of gardenia.

[0032] 2. The preparation method of the natural composition

[0033] Take an appropriate amount of components according to the formula, mix and pulverize them, mix them with pure water at a mass volume ratio of 1:5-10, soak for 1-2 hours, reflux at 70-90°C for 1-2 hours, collect the filtrate by filtration, and the filtrate is 3000r / The supernatant was collected by centrifugation for 1 min, the supernatant was concentrated under reduced pressure, dried and pulverized to remember the natural composition. Dosage: 100ml per day, take it twice in the morning and evening after meals, 7 days as a course of treatment.

Embodiment 2

[0035] 1. A natural composition for treating depression

[0036] The natural composition comprises the following raw materials in parts by weight: 5 parts of bupleurum, 20 parts of wild jujube seed, 20 parts of curcuma, 10 parts of citrus aurantium, 15 parts of jujube, 20 parts of mother-of-pearl, and 10 parts of gardenia.

[0037] 2. The preparation method of the natural composition

[0038] Take an appropriate amount of components according to the formula, mix and pulverize them, mix them with pure water at a mass volume ratio of 1:5-10, soak for 1-2 hours, reflux at 70-90°C for 1-2 hours, collect the filtrate by filtration, and the filtrate is 3000r / The supernatant was collected by centrifugation for 1 min, and the supernatant was concentrated under reduced pressure, dried and pulverized to obtain the natural composition. Dosage: 100ml per day, take it twice in the morning and evening after meals, 7 days as a course of treatment.

Embodiment 3

[0040] 1. A natural composition for treating depression

[0041] The natural composition comprises the following raw materials in parts by weight: 10 parts of bupleurum, 10 parts of wild jujube seed, 10 parts of curcuma, 5 parts of citrus aurantium, 30 parts of jujube, 30 parts of mother of pearl, and 5 parts of gardenia.

[0042] 2. The preparation method of the natural composition

[0043] Take an appropriate amount of components according to the formula, mix and pulverize them, mix them with pure water at a mass volume ratio of 1:5-10, soak for 1-2 hours, reflux at 70-90°C for 1-2 hours, collect the filtrate by filtration, and the filtrate is 3000r / The supernatant was collected by centrifugation for 1 min, and the supernatant was concentrated under reduced pressure, dried and pulverized to obtain the natural composition. Dosage: 100ml per day, take it twice in the morning and evening after meals, 7 days as a course of treatment.

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PUM

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Abstract

The invention discloses a natural composition for treating depression and a preparation method thereof. The natural composition includes the following raw materials in parts by weight: 5-10 parts of Bupleurum bupleurum, 10-20 parts of Suanzaoren, 10-20 parts of turmeric 20 parts, 5-10 parts of Citrus aurantium, 15-30 parts of jujube, 20-30 parts of mother-of-pearl, 5-10 parts of gardenia. The natural composition of the present invention contains a variety of active ingredients, which act synergistically on multiple targets of depression. The whole composition has the functions of improving the secretion of monoamine neurotransmitters in the brain, promoting the expression of neurotrophic factors, reducing the production of inflammatory factors, protecting The role of neurons has a good effect on the treatment of depression. The composition adopts natural medicinal resources as raw materials, has definite curative effect and has no toxic and side effects.

Description

technical field [0001] The invention relates to the technical field of natural compositions, in particular to a natural composition for treating depression and a preparation method thereof. Background technique [0002] Depression refers to a type of mood and affective disorder caused by various factors such as mood disorders and genetics, with significant and persistent depression and cognitive dysfunction as the main clinical features. It is characterized by high recurrence rate and high suicide rate, which is one of the global public health problems. Clinically, the main manifestations are depression, ranging from depressed to distraught, low self-esteem and depression, even pessimistic and world-weary, and even suicide attempts or behaviors in severe cases. Each attack lasts for at least 2 weeks, or even years in the elderly. Most cases have a tendency to recur, and some patients may have residual symptoms or turn into chronic depression. At present, there are still pr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P25/24A61K35/618
CPCA61K35/618A61K36/233A61K36/725A61K36/744A61K36/752A61K36/9066A61K2236/331A61K2236/51A61K2236/53A61P25/24A61K2300/00
Inventor 刘浩余龙江付春华金文闻兰广毅郭昊天罗涵任多豪熊俊浩
Owner EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH
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