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Heparin-like composition containing flushing agent

The technology of a composition and a flushing agent is applied in the field of flushing agents containing a heparinoid composition, which can solve the problems such as the imperfect application of the heparinoid composition, and achieves inhibition of smooth muscle cell reproduction, promotion of supply and waste excretion, and inhibition of excessive growth. Effect

Inactive Publication Date: 2019-03-22
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A flushing agent containing a heparinoid composition, including 30 parts of heparinoid, 66 parts of water for injection, 0.1 part of dimethyl sulfoxide, 3 parts of glycerin, 0.6 part of vitamin C, 0.1 part of potassium sorbate, p-hydroxybenzoic acid 1 part of methyl ester, 1 part of ethyl p-hydroxybenzoate.

Embodiment 2

[0026] A flushing agent containing heparin composition, including 10 parts of heparin, 67 parts of water for injection, 1 part of dimethyl sulfoxide, 10 parts of glycerin, 0.125 parts of vitamin C, 0.125 parts of potassium sorbate, p-hydroxybenzoic acid 0.1 part of methyl ester, 0.08 part of ethyl p-hydroxybenzoate.

Embodiment 3

[0028] A flushing agent containing heparin composition, including 5 parts of heparin, 66.5 parts of water for injection, 2 parts of dimethyl sulfoxide, 15 parts of glycerin, 0.2 parts of vitamin C, 0.2 parts of potassium sorbate, p-hydroxybenzoic acid 2.5 parts of methyl ester, 2.5 parts of ethyl p-hydroxybenzoate.

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PUM

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Abstract

The invention discloses a heparin-like composition containing a flushing agent, and belongs to the field of biotechnology. The heparin-like composition containing the flushing agent is characterized by comprising 0.01-30 parts of mucopolysaccharide, 0.01-5 parts of an isoosmotic regulator, 0.01-5 parts of an antioxidant, 0.01-5 parts of a bacteriostatic agent, 0.01-15 parts of a surfactant, 0.01-5parts of a preservative and 20-67 parts of a solvent. Under a synergistic action of a keratin softening agent and a natural moisturizing agent, the heparin-like composition containing the flushing agent can inhibit the excessive growth of collagen fiber and reduce scar formation; the heparin-like composition containing the flushing agent can retain moisture on the surface of skin to soften the collagen fiber and enhance the elasticity and has an effect of softening a hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a flushing agent containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a rol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K47/22A61K31/726A61K31/727A61K31/737A61P29/00A61P31/04A61P31/10A61P31/12A61P7/10A61P17/02
CPCA61K9/0014A61K9/08A61K31/726A61K31/727A61K31/737A61K47/22A61P7/10A61P17/02A61P29/00A61P31/04A61P31/10A61P31/12
Inventor 唐财坤关云成李丹胡莹满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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