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Traditional Chinese medicine composition for treating depression and pharmaceutical combination and applications thereof

A composition and technology for depression, applied in the direction of drug combination, medical raw materials derived from mollusks, pharmaceutical formulations, etc., can solve problems such as difficult to obtain effects, serious adverse drug reactions, etc., achieve less dosage, alleviate or control the disease. Progression, effect with few side effects

Active Publication Date: 2019-04-12
陕西省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the serious adverse reactions of drugs, some patients have strong resistance to drugs, and it is difficult to obtain satisfactory results in clinical application.

Method used

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  • Traditional Chinese medicine composition for treating depression and pharmaceutical combination and applications thereof
  • Traditional Chinese medicine composition for treating depression and pharmaceutical combination and applications thereof
  • Traditional Chinese medicine composition for treating depression and pharmaceutical combination and applications thereof

Examples

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Comparison scheme
Effect test

preparation example Construction

[0063] The preparation method of the traditional Chinese medicine composition of the present invention, as mentioned above, can be a decoction method, and can also be a powder preparation method. These preparation methods are scientific and reasonable, without any additives, and the preparation methods are simple and easy, so that patients can take them healthier. Especially the powder obtained by the powder preparation method, in terms of taking method, for long-term business trips and patients with busy work, the traditional decoction method is changed, and the above-mentioned natural pure Chinese herbal medicine is rationally formulated, ground into powder, and jujube, lily, honey As a medicine primer, lead all medicines directly to the sick place, and play a better role. The traditional Chinese medicine has the advantages of low price, simple preparation, definite curative effect and no toxic or side effect.

[0064] In a second aspect, the present invention provides a dr...

Embodiment 1

[0077] Embodiment 1. Formula and preparation of Chinese medicine composition

[0078] Chinese medicine composition 1, which is prepared from the following raw materials in parts by weight: 10 parts of angelica, 20 parts of white peony, 10 parts of Bupleurum, 10 parts of wine skullcap, 10 parts of gardenia, 10 parts of tempeh, 15 parts of schisandra, Radix Ophiopogon japonicus 15 parts, 10 parts of green lily, 30 parts of purple bay tooth, 20 parts of wild jujube seed, 30 parts of night cross vine, 30 parts of floating wheat, 6 parts of jujube, and 6 parts of roasted licorice.

[0079] Chinese medicine composition 2, which is prepared from the following raw materials in parts by weight: 20 parts of angelica, 30 parts of white peony, 10 parts of Bupleurum, 15 parts of wine skullcap, 15 parts of gardenia, 15 parts of tempeh, 15 parts of schisandra, Radix Ophiopogon japonicus 20 parts, 15 parts of green lily, 30 parts of purple bay tooth, 30 parts of wild jujube seed, 30 parts of ...

Embodiment 2

[0088] Embodiment 2. The clinical trial of Chinese medicine composition of the present invention

[0089] 1. Clinical data:

[0090] The traditional Chinese medicine composition of the present invention is used to treat 90 patients with depression and insomnia clinically. The 90 patients were randomly divided into a Western medicine group of 35 cases, a Chinese medicine group of 20 cases, and a Chinese and Western medicine combination group of 35 cases, including 39 males and 51 females, aged between 35 and 75 years old, and the shortest course of disease was 6 months , up to 22 months. All patients were evaluated with a total score of ≥8 points by HAMD (Hamilton Depression Rating Scale), and a standard score of ≥53 points by SDS (Self-Rating Depression Scale). There was no statistical difference between the two groups in terms of gender, age, course of disease, past history, and scores of various scales before treatment (P>0.05), suggesting that the baselines were even and ...

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Abstract

The invention belongs to the field of traditional Chinese medicine. More particularly, the invention relates to a traditional Chinese medicine composition for treating depression and a pharmaceuticalcombination and applications thereof. The traditional Chinese medicine composition of the present invention is made of 15 traditional Chinese medicines, and is prepared from natural pure plants and animals as sources. Compared with the prior art, the composition follows the tradition, has the functions of relieving depression, nourishing blood and calming nerves, can effectively alleviate or control the progress of the disease with low dosage, fined formula and small side effects, and can achieve the curing effect after long-term use. In addition, the preparation method of the invention is scientific and reasonable and free from additive, and the preparation method is simple and easy, so that the patients are healthier after using the composition. Furthermore, the traditional Chinese medicine composition of the present invention plays a significant synergistic effect when used in combination with conventional western medicines used for treating depression.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for treating depression, its medicine combination and application. Background technique [0002] Depression, also known as depressive disorder, is a common clinical disease today, and it is a mood disorder of patients. [1] . The main clinical features are marked and persistent depression, decreased mobility, and slow thinking and cognitive functions. With the rapid development of modern society, people's pace of life is constantly accelerating, and the huge life pressure makes the incidence of depression increase year by year. Although depression is mostly mild to moderate, if it is not handled properly, it will aggravate the condition of patients with depression, causing obvious anxiety and exercise agitation, and even suicidal behavior. Patients with depression have a very high disability rate and recurrence rate, w...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/24A61K31/135A61K31/4525A61K31/496A61K35/618
CPCA61K31/135A61K31/4525A61K31/496A61K35/618A61K36/232A61K36/233A61K36/48A61K36/484A61K36/539A61K36/57A61K36/65A61K36/704A61K36/71A61K36/725A61K36/744A61K36/79A61K36/896A61K36/8968A61K36/899A61P25/24A61K2300/00
Inventor 雷亚玲陈钧袁捷阮绍萍曹瑾
Owner 陕西省中医医院
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