Intestinal mitochondrial functional protector for alleviating heat stress in broiler chickens

A mitochondrial and heat stress technology, applied in application, animal feed, additional food elements, etc., can solve problems such as unreported, and achieve the effect of increasing residence time, improving intestinal mitochondrial function, and alleviating intestinal mitochondrial function damage

Active Publication Date: 2019-04-30
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, studies on the regulation of mitochondrial function through nutritional means are rare, and studies on the improvement of mitochondrial function through regulation of mitophagy have not been reported.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0019] Preparation: the palygorskite used below is a palygorskite powder with a particle size (200 mesh passing rate) of 92% and a blue absorption of 18g / 100g.

[0020] Take 5 kg of ginkgo biloba extract, 6 kg of chlorogenic acid, 5 kg of betaine, and 10 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving heat stress in broilers. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.05wt.%.

[0021] 105 21-day-old Ross 308 broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, ginkgo leaf extract group (heat stress + ginkgo leaf extract), chlorogenic acid group (heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in the heat-neut...

Embodiment 2

[0027] Preparation: the palygorskite used is palygorskite powder with a particle size (200 mesh passing rate) of 94% and a blue absorption of 18g / 100g.

[0028] Take 2 kg of Ginkgo biloba extract, 2 kg of chlorogenic acid, 2 kg of betaine, and 5 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving broiler heat stress. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.15wt.%.

[0029]In the experiment, 105 14-day-old AA broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, ginkgo leaf extract group (heat stress + ginkgo leaf extract), chlorogenic acid group ( heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in the heat-neut...

Embodiment 3

[0035] Preparation: the palygorskite used is palygorskite powder with a particle size (200 mesh passing rate) of 97% and a blue absorption of 24g / 100g.

[0036] Take 8 kg of ginkgo biloba extract, 9 kg of chlorogenic acid, 8 kg of betaine, and 15 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving heat stress in broilers. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.10wt.%.

[0037] In the experiment, 105 21-day-old Avian broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, Ginkgo biloba extract group (heat stress + Ginkgo biloba extract), chlorogenic acid group ( heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in ...

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PUM

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Abstract

The invention discloses an intestinal mitochondrial functional protector for alleviating heat stress in broiler chickens, wherein the intestinal mitochondrial functional protector consists of 5-10 parts by weight of a ginkgo leaf extract, 6-10 parts by weight of chlorogenic acid, 5-10 parts by weight of betaine and 10-25 parts by weight of palygorskite. Compared with addition of the ginkgo leaf extract, chlorogenic acid, betaine and palygorskite separately in a feed, the protector can significantly alleviates heat stress in the broiler chickens, significantly increases the intestinal mitochondrial autophagy level under heat stress in the broiler chickens and improves intestinal mitochondrial functions of heat stress in the broiler chickens. The four components have significant interactionin increasing mitochondrial function of the broiler chickens and mitochondrial autophagy level, and have positive synergistic combined effect. The palygorskite has controlled-release effect on the ginkgo leaf extract, chlorogenic acid and betaine, the ginkgo leaf extract, chlorogenic acid and betaine are allowed to be easily mixed with a feed, a uniform dispersion system is formed and use is convenient. Through the synergistic effect of all the components, the level of mitochondrial autophagy under heat stress in the broiler chickens is significantly improved, and the intestinal mitochondrialfunction injury caused by heat stress is significantly alleviated.

Description

technical field [0001] The invention relates to an intestinal mitochondrial function protective agent for alleviating broiler chicken heat stress. Background technique [0002] During modern intensive farming, poultry are often subjected to various stresses, which lead to increased morbidity and stunted growth of poultry. Among the many stress factors, the ambient temperature is particularly important. Poultry is an animal sensitive to heat stress. With the intensification and scale of poultry farming and global warming, the harm of heat stress to poultry has become more and more prominent. Studies have shown that excessively high temperatures can cause a series of symptoms in poultry, such as reduced growth performance, impaired intestinal barrier function, slowed growth in mild cases, decreased resistance, and death in severe cases, resulting in major economic losses. [0003] The intestine is the digestive organ of the body, and it also has endocrine and immune function...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/75A23K10/30A23K20/105A23K20/142A23K20/28
CPCA23K10/30A23K20/105A23K20/142A23K20/28A23K50/75
Inventor 胡彩虹王春春冯杰曹舒婷
Owner ZHEJIANG UNIV
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