A photoelectrochemical method for the detection of cancer cells by self-assembled organic semiconductor material pc05 nanowires

Abstract

The invention discloses a photo-induced electrochemical immunosensor for detecting cancer cells based on the self-assembled organic semiconductor material PC05 nanowire structure. The length of a nanowire is regulated by using a simple self-assembling method and the nanowire with the most suitable length is selected. The organic semiconductor nanowire has the perfect crystal structure to realize the charge transport well. Meanwhile, gold nanoparticles are deposited on the electrode by electrodeposition and the Fermi level of gold matches the PC05 nanowire well, so that the photoelectric signalof the sensor is enhanced. Moreover, because of the PC05 as a p type semiconductor, the dissolved oxygen in the detection solution can consume the excited electrons in photoelectric testing.

Description

technical field

[0001] The invention relates to the field of quantitative detection of tumor markers, more specifically to the photoelectrochemical detection of cancer cells based on the self-assembled organic semiconductor material Cobalt(II)-meso-tetra(4-carboxyphenyl)porphyrin (PC05) nanowire structure Construction of the immunosensor. Background technique

[0002] In recent years, the morbidity and mortality of cancer have gradually increased, and this trend is still increasing. Cancer cells refer to a new organism produced by some cells with the potential to divide under carcinogenic factors. In addition to their own uncontrolled growth, cancer cells can also invade the surrounding normal tissues and even transfer to other parts of the body through the body's circulatory system or lymphatic system, thereby causing body diseases and even death. Therefore, it is urgent to develop a sensor with high sensitivity and stability to realize the early diagnosis of cancer. [...