Application of Aconitine in the Preparation of Drugs for Treating Irritable Bowel Syndrome

Abstract

The invention belongs to the field of biomedicine and discloses a new application of aconitin in the preparation of medicines for treating irritable bowel syndrome. When the aconitin is applied to the treatment of irritable bowel syndrome, it can effectively alleviate the problems of visceral pain, mental anxiety and hyperalgesia caused by irritable bowel syndrome, and it is safe and effective.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to the application of aconitin in the preparation of medicines for treating irritable bowel syndrome (IBS). Background technique [0002] Irritable bowel syndrome (IBS) is defined as recurrent symptoms of visceral pain or a syndrome associated with altered bowel habits, characterized by abdominal pain, bloating, diarrhea, or constipation, of unknown etiology. IBS is the most common type of functional gastrointestinal disorder, and its clinical manifestations are mainly manifested in chronic abdominal intermittent or persistent hyperalgesia, changes in bowel emptying habits, and often accompanied by symptoms of anxiety. Emotional factors, diet, drugs, or hormones can trigger or exacerbate this high-tonic GI motility. Some IBS patients have anxiety disorders, especially phobias, adult depression, and somatic symptomatization disorders. Currently, there is no clear and effective...

AI Technical Summary

Problems solved by technology

[0004] At present, many drugs for the treatment of IBS on the market have adverse reactions. For example, although anticholinergic drugs can relieve abdominal pain and stop diarrhea, they can easily cause abdominal distension, and long-term use will lead to drug dependence, which will increase the intractability of constipation

For the relief of abdominal pain symptoms and psychogenic symptoms such as anxiety, there is no effective drug or optional combination drug

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