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Fresh ginger and turmeric extract composition for improving helicobacter pylori in gastrointestinal tracts

A technology of ginger extract and turmeric extract, applied in the field of ginger and turmeric composition, can solve the problems of not particularly prominent effect, affecting taking experience, poor taste and the like

Inactive Publication Date: 2019-05-07
上海航禹生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of ginger and turmeric alone to treat pain is relatively large, the effect is not particularly outstanding, and the taste is not good, which affects the taking experience

Method used

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  • Fresh ginger and turmeric extract composition for improving helicobacter pylori in gastrointestinal tracts
  • Fresh ginger and turmeric extract composition for improving helicobacter pylori in gastrointestinal tracts
  • Fresh ginger and turmeric extract composition for improving helicobacter pylori in gastrointestinal tracts

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Example 1: Ginger and Turmeric Composition

[0050] This example provides three ginger and turmeric compositions with different formulation contents.

[0051] The formula ratio of the cassia pepper ginger analgesic composition is: ginger extract: turmeric extract: black plum extract: glutamine: L-arabinose can be 10-60%: 5%-60%: 10%-50 %: 3%-30%: 10-30%.

[0052] See Table 1 for examples of three formulations. The proportions of ginger extract, turmeric extract, ebony extract, glutamine and L-arabinose in formula 3 are 52%: 10%: 13%: 5%: 20%.

[0053] Table 1. Recipe

[0054]

Embodiment 2

[0055] Embodiment 2: the antibacterial experiment of ginger and turmeric composition

[0056] In this example, the NACL group, the control group and the experimental group were used to carry out antibacterial experiments.

[0057] experimental method:

[0058] In this implementation, the formula of the NACL group is: 5% normal saline; the formula of the control group is: 30 mg of turmeric, 300 mg of glutamine, and 170 mg of dextrin; the formula of the experimental group is formula 3 in Example 1.

[0059] The Hp strain was the internationally unified SS1 (Sydney Strain1) strain, which was identified as cagA(+) and VacA(+). The solid medium is the modified Skirrow selective medium, that is, the antibiotic mixture is added to the 1000ml modified Skirrow agar base, so that the final concentration is tetracycline (TMP) 5mg / L, vancomycin 10mg / L, polymyxin B 2 500U / L, and add 50ml of defibrinated frozen-thawed rabbit blood.

[0060] Dissolve the formula, centrifuge at 3 500r / m...

Embodiment 3

[0067] Embodiment 3: Animal experiments for improving gastric mucosal damage

[0068] In this embodiment, the formulas of model group, control group and experimental group are used to carry out animal experiments, wherein the animals are rats.

[0069] 24 SD rats (half male and female) weighing 180-220g were placed in small cages every eight, and were divided into three groups, model group, control group and experimental group. The formula of the model group is 500 mg of dextrin; the formula of the control group is: 30 mg of turmeric, 300 mg of glutamine, and 170 mg of dextrin; the formula of the experimental group is formula 3 in Example 1.

[0070] After 24 hours of fasting, 0.2g / kg of the control formula and the experimental formula were administered orally, and 2.35g / kg of absolute ethanol was administered orally after 24 hours, and the animals were sacrificed 1 hour later, and the stomach was taken out by laparotomy, and cut from the pylorus to the cardia. Open it, was...

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Abstract

The invention discloses a fresh ginger and turmeric composition. The composition includes a fresh ginger extract product, a turmeric extract product, a dark plum extract product, glutamine and L-arabinose; the composition is used for treating gastrointestinal diseases, especially for inhibiting helicobacter pylori; and the composition can obviously inhibit the helicobacter pylori, so that the symptoms of the gastrointestinal diseases can be improved.

Description

technical field [0001] The present invention relates to a ginger and turmeric composition for improving gastrointestinal diseases. Specifically, the present invention relates to a ginger and turmeric composition comprising ginger, turmeric, ebony, glutamine, and L-arabinose for inhibiting Helicobacter pylori. Background technique [0002] Helicobacter pylori (Hp) was first isolated and cultured successfully from the gastric antrum mucosa biopsy tissue of patients with chronic active gastritis in 1982 by Warren and Marshall. Malignant lymphoma of mucosa-associated lymphoid tissue (MALT) is closely related to intestinal-type gastric cancer, and WHO listed it as a class I biological carcinogen for gastric cancer in 1994 [1]. According to the survey, Hp infection is widespread in the world, the world average infection rate is about 50%, and the Hp infection rate (adults) in natural populations in all parts of my country is above 50%. Western medicine uses antibiotic-based trip...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04A61P31/04A61K31/198A61K31/7004
Inventor 孙涛孟学海
Owner 上海航禹生物科技有限公司