Application of 2-cycloamino fatty diacid derivative in preparing animal feed additives

A technology of cyclic amino fats and derivatives, which is applied in the application field of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives, can solve the problems such as the use of compounds that are rarely reported, and achieve the goal of improving animal growth and feed remuneration Effect

Active Publication Date: 2019-05-10
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] 2-Cyclic amino fatty diacids are a class of compounds produced by the Michael addition reaction of α,β-unsaturated diacids and cyclic ammonia. From 1962 to 2016, researches have reported the synthesis, purification and Structural characterization and other methods, but the use of such compounds is rarely reported

Method used

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  • Application of 2-cycloamino fatty diacid derivative in preparing animal feed additives
  • Application of 2-cycloamino fatty diacid derivative in preparing animal feed additives
  • Application of 2-cycloamino fatty diacid derivative in preparing animal feed additives

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] Example 1 Effect of 2-cycloamino fatty diacid derivatives on production performance of pigs

[0152] 300 piglets of 65-day-old "Du Dachang" three-way crossbreed lean meat with similar body weight were randomly divided into 10 treatment groups, with 3 replicates in each group, 10 pigs in each replicate, half male and half female. The pigsty and utensils were disinfected before the experiment. During the test period, the pigs were reared in separate pens under the same feeding and management conditions in the same pen. During the test period, the test pigs had free access to food and water, and were fed twice a day. Each test group is the control group (group 1) and test groups 2-10. Among them, the control group was only given the basal diet, and the experimental groups 2 to 10 were given the rations added with 100 ppm of different 2-ring amino fatty diacid derivatives on the basis of the basal diet, as shown in Table 1.

[0153] During the whole feeding process, no o...

Embodiment 2

[0164] Example 2 Effect of 2-cycloamino fatty diacid derivatives on broiler performance

[0165]The experiment adopts a single factor random design, selects 960 three-yellow-feathered broiler chickens with an average body weight of 50 g at the age of 1 day and similar body weight, and randomly divides them into 10 treatment groups, with 6 replicates in each group, half male and half female, and 16 male and female chickens in each replicate. Only three yellow-feathered broilers. The chicken coop and utensils were disinfected before the experiment. During the experimental period, cages were carried out under the same feeding and management conditions in the same chicken house. The basic diet is mainly corn-soybean meal, and no other antioxidant ingredients and growth promoters are added during the whole feeding process. Each test group is the control group (group 1) and test groups 2-10. The control group was only given basal rations, and 50 ppm of different 2-ring amino fatt...

Embodiment 3

[0173] Example 3 Application of 2-cyclic amino fatty diacid derivatives in fish feed

[0174] The fish used in the experiment was grass carp, which was carried out by the Aquatic Farm of Guangzhou Ensaite Experimental Field. Healthy and lively grass carp fingerlings with consistent specifications were raised in large cages for 4 weeks before being used for formal breeding experiments. The experimental system was small floating cages. The small cages and temporary cages are placed in a 3500m test field 2 In the pond, the depth of the pond is about 1.5m, and the pond water is fully aerated bottom water. During the experiment, 420 grass carp that were starved for 1 day were randomly divided into 7 groups, each group had 4 replicates, and 15 fish were placed in each replicate. After the overall weighing, they were randomly put into 28 cages, and fed with different test feeds. . Each test group is the control group (group 1) and test groups 2-7. The experimental feed was self-p...

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Abstract

The invention discloses application of 2-cycloamino fatty diacid derivatives represented as formula (I), or racemes, stereo isomers, geometric isomers, tautomer and solvent compounds thereof, or acceptable salt of feed thereof in preparing animal feed additives, wherein B is C0-C9 alkylene; R1 and R2 are C1-C20 alkyl or H; A is CH2, N, S or O; Z is C0-C3 alkylene, Y is C2-C4 alkylene and R3 is -OH,-NH2,-NO2,-CN,-SH,-X, -C1-C5 alkoxy, -C1-C5 alkylene or -C1-C5 alkylene substituted by X, wherein X is selected from F, Cl, Br or I; N is chosen from natural numbers of 0-5. According to animal breeding experiment results shown in the description, the 2-cycloamino fatty diacid derivatives can be used as animal feed additives, and has good effects on improving production performance such as animalgrowth and feed yield.

Description

technical field [0001] The invention relates to the field of animal feed additives, in particular to the application of a 2-cycloamino fatty diacid derivative in the preparation of animal feed additives. Background technique [0002] Feed additives refer to small or trace substances added during feed processing, production and use, including nutritional feed additives and general feed additives. Among them, the general feed additive refers to a small or trace amount of substances mixed into the feed to ensure or improve the quality of the feed and increase the utilization rate of the feed. At present, commonly used general feed additives that can efficiently and stably increase feed utilization and improve animal production performance mainly include: high-dose copper, high-dose zinc, feed antibiotics, chemically synthesized antibacterial agents, etc. However, the long-term use of these substances in the breeding industry will produce relatively large side effects, such as ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/132A23K20/137A23K50/30A23K50/60A23K50/75A23K50/80
Inventor 彭险峰
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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