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In vitro dual-dynamic degradation performance monitoring device for medical magnesium alloy implantable device

A technology for magnesium alloys and devices, which is applied in the field of devices for monitoring the dual dynamic degradation performance of medical magnesium alloy implants in vitro. The effect of contact error, reducing error interference, and improving accuracy

Pending Publication Date: 2019-05-17
ZHEJIANG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These in vitro dynamic tests often only provide simulated circulation of body fluids, but do not fully simulate the real environmental conditions of the human body, making it difficult to accurately measure the degradation rate and monitor the entire in vitro degradation process in real time.
The in vitro static immersion test is to statically immerse medical magnesium alloy implants in simulated body fluids to study the in vitro degradation performance of magnesium alloy implants, and further speculate on their degradation performance in the human body; often such in vitro static immersion The experiment is even more unable to fully simulate the real special environment in the human body, ignoring the effects of the constant temperature environment in the human body, the flow of body fluids, and the self-movement of human tissues and organs on the corrosion and degradation of medical magnesium alloy implants. At the same time, it is impossible to monitor the dynamic corrosion in vitro During the degradation process, the temperature, pH value and electrochemical characteristics of the body fluid are simulated. In the general in vitro static immersion experiment, the cumbersome method of drying and weighing the sample is used to roughly calculate the static degradation rate, and it is impossible to make a more accurate guess. The in vitro degradation rate; the static immersion test process is simple and direct, but the error is large. It cannot provide an in vitro simulation environment that simulates different flow rates of body fluids, constant temperature environments, and real movement of human tissues and organs, and cannot monitor and analyze its in vitro degradation performance in real time. It is difficult to be more accurate Estimating its degradation rate, consumes a lot of manpower, material resources and financial resources

Method used

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  • In vitro dual-dynamic degradation performance monitoring device for medical magnesium alloy implantable device
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  • In vitro dual-dynamic degradation performance monitoring device for medical magnesium alloy implantable device

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Embodiment Construction

[0057] The technical solution of the present invention will be further described below in conjunction with the accompanying drawings.

[0058] see figure 1 , image 3 , Figure 4 , Figure 5 The device of the present invention consists of a base 1, a computer 2, a first control line 3, a motor support base 4, a reducer 5, a motor 6, a shaft coupling 7, a rotating disk 8, a first pin 9, a first connecting rod 10, Second pin 11, second connecting rod 12, second connecting rod support frame 13, third pin 14, fourth pin 15, third connecting rod 16, bolt 17, active magnetic assembly 18, sample slot 19, to be tested Device 20, driven magnetic assembly 21, pH meter 22, thermometer 23, sample tank support seat 24, pipe 25, hydrogen sensor 26, measuring cylinder 27, liquid storage tank 28, constant temperature tank 29, circulation pump 30, circulation pump support frame 31. A flow meter 32, a second control line 33, an electrode 34, a test line 35, an electrochemical workstation 36...

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Abstract

The invention provides an in vitro dual-dynamic degradation performance monitoring device for a medical magnesium alloy implantable device. The device realizes a controllable environment for simulating the movement of human tissues and organs in vitro of the medical magnesium alloy implantable device through the combined action of a motor, a speed reducer, a rotating disc, a crank connecting rod mechanism, a driving magnetic component, a driven magnetic component and a computer, and the in vitro constant temperature dynamic simulation environment of the medical magnesium alloy implantable device is completed through the combined action of a circulating pump, a flowmeter, a sample tank, a constant-temperature tank, a liquid storage tank, a pipeline and the computer; temperature and pH changes during the in vitro dual-dynamic corrosion degradation process are monitored by using a thermometer and pH meter; the dual-dynamic degradation rate is visually characterized by using a hydrogen evolution method; the degradation performance and the degradation rate are monitored and analyzed by using the combined action of an electrochemical workstation and the computer; and a stable and reliable monitoring device is provided for the in vitro dual-dynamic degradation performance analysis of the medical magnesium alloy implantable device, which greatly improves the possibility of medical industrialization of magnesium alloys.

Description

technical field [0001] The invention relates to a monitoring device for analyzing the degradation performance of medical devices in a simulated real environment of a human body, specifically a device for monitoring the double dynamic degradation performance of medical magnesium alloy implanted devices in vitro. Background technique [0002] With the increasing aging of the social population and the various injuries caused by various diseases and accidents caused by humans, people have greatly improved their requirements for medical quality, which has led to the development and application of medical implants. Researchers have increased their research on medical implant devices, and medical magnesium and magnesium alloy material devices have emerged as the times require. Magnesium and magnesium alloys have the advantages of good mechanical compatibility, biocompatibility, and degradability in human body fluids, making their application in the field of medical degradable devic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/416
Inventor 熊缨朱涛沈永水杨杰何留永
Owner ZHEJIANG UNIV OF TECH
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