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Traditional Chinese medicine composition used for treating myelodysplastic syndrome and preparation method and application thereof

A technology for myelodysplasia and composition, applied in the field of medicine, can solve the problems of difficult promotion, non-recommendation, high cost, etc., and achieve the effects of wide application value, good therapeutic effect, and no toxic and side effects

Inactive Publication Date: 2019-05-31
苏凤哲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chemotherapy and hematopoietic stem cell transplantation are generally not recommended for the low-risk group. The prognosis for the high-risk group is poor. Chemotherapy and hematopoietic stem cell transplantation are options, but the complications and mortality are relatively high
[0004] In recent years, a lot of research has been carried out on the treatment of MDS, and some new countermeasures for the proliferation and evolution of malignant clones have also emerged, which have played a certain role in solving the occurrence of complications and transformation to leukemia, but there are differences in individualized treatment. Sex is still very large, and expensive, it is more difficult to promote

Method used

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  • Traditional Chinese medicine composition used for treating myelodysplastic syndrome and preparation method and application thereof
  • Traditional Chinese medicine composition used for treating myelodysplastic syndrome and preparation method and application thereof
  • Traditional Chinese medicine composition used for treating myelodysplastic syndrome and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Take 15g bamboo ginseng, 12g antler cream, 12g privet fruit, 12g psoraleae, 15g five-clawed dragon, 12g gorse root, 15g winter grass, 20g sheep's heel, 3g pangolin, 12g barbata, add 600mL of water , then decocted for 30 minutes, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; added 400mL of water to the medicinal residue, decocted for 20min, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; Get it after the merger.

Embodiment 2

[0021] Take 10g bamboo ginseng, 10g antler cream, 10g privet privet, 10g psoralen, 10g five-clawed dragon, 10g gorse root, 10g winter grass, 15g sheep's heel, 1g pangolin, 10g barbata, add 600mL of water , then decocted for 30 minutes, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; added 400mL of water to the medicinal residue, decocted for 20min, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; Get it after the merger.

Embodiment 3

[0023] Take 20g bamboo ginseng, 15g antler cream, 15g privet fruit, 15g psoraleae, 20g five-clawed dragon, 15g gorse root, 20g winter grass, 25g sheep's heel, 5g pangolin, 15g Scutellaria barbata, add 600mL of water , then decocted for 30 minutes, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; added 400mL of water to the medicinal residue, decocted for 20min, decocted until the remaining 200mL of the medicinal liquid, filtered out the medicinal liquid; Get it after the merger.

[0024] After the liquid medicine is obtained, according to the needs of different preparations, suitable pharmaceutical excipients can be added to the obtained liquid medicine, and according to the conventional preparation process, it can be made into tablets, capsules, granules, mixtures, oral liquids or syrups, etc. dosage forms.

[0025] There is no record of the disease name of myelodysplastic syndrome in the ancient literature of traditional Chinese...

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Abstract

The invention discloses a traditional Chinese medicine composition used for treating myelodysplastic syndrome and a preparation method and application thereof. The traditional Chinese medicine is prepared from panacis japonici rhizome, cornu cervi degelatinatum, glossy privet fruits, fructus psoraleae, cairo morningglory roots, caragana roots, herba rabdosiae, rumex japonicus houtt roots, pangolinscales and barbated skullcup herbs. According to the traditional Chinese medicine composition used for treating the myelodysplastic syndrome, all the traditional Chinese medicinal materials cooperatewith one another and achieve the synergy effect according to the compatibility relationship of 'monarch, minister, adjuvant and envoy', thereby acting on the focus, and the effect of treating myelodysplastic syndrome is exerted. The clinical experiment proves that the traditional Chinese medicine composition has a good effect of treating the myelodysplastic syndrome, the total effective rate is 76.7%, the curative effect is stable, the myelodysplastic syndrome cannot easily relapse, and the traditional Chinese medicine composition has no toxic and side effects and has high application value.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese medicine composition for treating myelodysplastic syndrome and its preparation method and application. Background technique [0002] Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder. It is characterized by hematopoiesis, one or more lineages of myeloid cells, ineffective hematopoiesis and high risk of transformation to leukemia. Most MDS are characterized by progressive bone marrow failure, and the disease eventually develops into leukemia, but the probability of transformation into leukemia is different for different subtypes, and some of them show indolent development, and the rate of leukemia transformation is low. The incidence of this disease has shown an increasing trend in recent years. The incidence rate is about 4-12 / 100,000, and it is as high as 20-35 / 100,000 for those over 70 years old. There are more men ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61P7/00A61P19/08A61K35/32A61K35/36
Inventor 苏凤哲苏博洋
Owner 苏凤哲