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Dried dioscorea alata tuber granules and preparation method thereof

A technology of formula granules and ginseng potato is applied in the directions of pharmaceutical formulas, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., to achieve the effects of easy industrialization, improved stability and convenient taking.

Inactive Publication Date: 2019-06-07
JIANGXI GROUNDIONG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report about the ginseng and potato formula granules and its preparation process at present.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0020] The preparation method of ginseng and potato formula granules of the present invention comprises the following steps:

[0021] (1) Take ginseng and potato medicinal materials, add 8-10 times the amount of water, heat and decoct for 1-3 hours, extract 2-3 times, filter, and the filtrate is concentrated under reduced pressure to a relative density of 1.1-1.2 (based on the concentration of water 1g / cm 3 ) thick paste, get ginseng potato extract;

[0022] (2) Take the ginseng potato extract, add an appropriate amount of pharmaceutically acceptable auxiliary materials for mixing, dry, collect the dry paste powder, pulverize through an 80-mesh sieve, and mix in a mixing tank;

[0023] (3) Take ginseng potato paste powder, granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh sieve in turn to obtain ginseng-potato formula granules.

[0024] In step (1), in terms of volume, the amount of water fed is 8-10 times that of ginseng and potato medicinal materials...

Embodiment 1

[0038] (1) Take 1 kg of ginseng and potato herbs, add 9 times the amount of water, heat to 90 ° C for 2 hours, extract twice, filter through 200-mesh stainless steel mesh, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.1 , get ginseng potato extract;

[0039] (2) Take the ginseng potato extract, add 100g of starch, lactose and dextrin mixture (the weight ratio of the three is 1:0.25:1) for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it tank mix;

[0040] (3) Take ginseng potato paste powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh sieve in turn to obtain the ginseng-potato formula granule sample A1.

Embodiment 2

[0042] (1) Take 1 kg of ginseng and potato medicinal materials, add 8 times the amount of water, heat to 85 ° C for 3 hours, extract 3 times, filter with 200-mesh stainless steel wire mesh, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.2 , get ginseng potato extract;

[0043] (2) Take the ginseng potato extract, add 80g of a mixture of starch, lactose and dextrin (the weight ratio of the three is 1:0.25:1) for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it tank mix;

[0044] (3) Take ginseng potato cream powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh sieve in turn to obtain the ginseng-potato formula granule sample A2.

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Abstract

The invention relates to the technical field of traditional Chinese medicine formula granules, and discloses dried dioscorea alata tuber granules and a preparation method thereof. The method comprisesthe following steps of (1) taking dried dioscorea alata tuber medicinal materials, adding water which is 8-10 times of the dried dioscorea alata tuber medicinal materials, performing heating and decoction for 1-3 hours, performing extraction for 2-3 times, performing filtration, and performing decompressed concentration on filtrate to obtain thick paste of which the relative density is 1.1-1.2 toobtain a dried dioscorea alata tuber extract; (2) taking the dried dioscorea alata tuber extract, adding an appropriate quantity of pharmaceutically acceptable auxiliary materials, performing mixing,performing drying, collecting dried paste powder, performing crushing, performing screening with an 80-mesh sieve, and placing powder in a mixing tank for mixing; and (3) taking the dioscorea alata tuber cream powder, performing granulation, and sequentially granulating the granules with a 20-mesh sieve and a 50-mesh sieve, so as to obtain the dried dioscorea alata tuber granules. The dried dioscorea alata tuber granules prepared by the method disclosed by the invention have high active component content, and are uniform in granule size.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine formula granules, in particular to a ginseng and potato formula granule and a preparation method thereof. Background technique [0002] Traditional Chinese medicine formula granules are obtained by extracting, separating, concentrating, drying, granulating and packaging the whole ingredients of the medicinal materials through modern processing technology and pharmaceutical technology. They can be directly formulated and packaged without decoction. Granules for ingestion. Traditional Chinese medicine formula granules not only retain the active ingredients, indications and efficacy of traditional Chinese medicine decoction pieces, but also have the advantages that decoction pieces do not have, such as unified standard, stable curative effect, convenient carrying and easy adjustment. Over-the-counter supplements. [0003] Ginseng potato comes from the dry tuber of Dioscorea ala...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K47/36A61K47/26A61K36/8945A61P1/14A61P29/00
CPCA61K9/16A61K36/8945A61K47/26A61K47/36A61P1/14A61P29/00
Inventor 廖年生胡贤德眭荣春杨健平
Owner JIANGXI GROUNDIONG PHARM CO LTD
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