Online pretreatment device for hair sample injection

Abstract

The embodiments of the present invention provide an online pretreatment device for hair sample injection. The device is used for transferring hair samples during a pre-treatment process. The online pretreatment device for hair sample injection includes an image detector, a mass spectrometer, an objective lens and a sample cabin assembly; the sample cabin assembly includes a sample cavity and a plate drawer disposed within the sample cavity; the plate drawer slidably enters and withdraws from the sample cavity, the objective lens is connected between the mass spectrometer and the sample cabin assembly; and an image under the objective lens is shot through an image sensor and is transmitted to an external device. The online pretreatment device for hair sample injection of the invention adopted, the rapid qualitative and quantitative measurement of drugs or metabolic components thereof in hairs can be realized; samples are directly injected into a time of flight mass spectrometer; the time of flight mass spectrometer is connected in series with a triple-quadrupole mass spectrometer for quantification; and therefore, the online pretreatment device has the advantages of improved sensitivity and high detection speed.

Description

technical field [0001] The invention relates to the technical field of drug detection in hair, in particular to an online pretreatment device for sampling hair samples. Background technique [0002] After the human body injects or takes drugs, in addition to urine, other such as hair, sweat, feces, tears, nails, etc. will more or less contain the drug or the metabolite of the drug, so it can be used as a drug test. evidence. Among them, as long as the hair is not cut off, it can fully present the subject's drug use history in the past few months, which is considered to be one of the most effective methods at present. [0003] The prior art discloses a device for entering and exiting a sample target of a matrix-assisted laser analysis time-of-flight mass spectrometer. This technology installs a two-dimensional planar moving mechanism in the vacuum cavity, and installs a connecting rod jacking mechanism on the moving platform to realize Take and place the sample, and the sam...

AI Technical Summary

Problems solved by technology

This technology is first used for the rapid characterization of macromolecules such as bacteria, and can quickly determine what kind of bacteria the patient is infected with. However, this technology is not suitable for the characterization of drugs or drug metabolites in hair.

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