Inverted flow hemodiafiltration method and device, hemofiltration assembly and pipeline assembly thereof

Abstract

The invention discloses an inverted flow hemodiafiltration method. A blood pump generates negative pressure so that a part of dialysate is counter ultra-filtered into a hollow fiber membrane of a first hemofilter to form replacement fluid flowing out of the first hemofilter, and the other part of the dialysate flows out of a dialysate region of the first hemofilter and enters a dialysate region ofa second hemofilter for diafiltration; and the replacement fluid is mixed with blood, then enters a hollow fiber membrane of the second hemofilter driven by a blood pump and is diafiltered. The invention also discloses corresponding equipment, a hemofiltration assembly and a pipeline assembly. The blood pump drives blood to flow and generates negative pressure in the hollow fiber membrane of thefirst hemofilter to form the replacement fluid, the replacement fluid can dilute the blood, so that various toxins in the blood are more easily excreted by entering the dialysate through the hollow fiber membrane under the ultrafiltration of the second hemofilter. When the blood flow is low, the replacement fluid can replenish the blood and then perform dialysis ultrafiltration, thereby avoiding interruption of treatment of a hemodialysis machine and ensuring continuous operation of hemodiafiltration.

Description

technical field [0001] The invention relates to medical equipment, in particular to a reverse flow hemodialysis filtration method and device, a hemofiltration component and a pipeline component thereof. Background technique [0002] Blood purification includes hemodialysis (HD), hemofiltration (HF), hemodiafiltration (HDF) and the like. There are two ways to achieve traditional hemofiltration, one is to pump the replacement fluid into the blood through a pump, and enter the arterial jug of the blood line at the front end of the hemofilter (also known as the pre-dilution method); the other is the pump Into the venous pot of the blood line tube at the rear end of the blood outflow hemofilter (also called post-dilution method). The replacement fluid is cultivated manually or online by a hemofiltration machine (commonly known as a double-pump machine). The process is to mix the dialysis concentrate at a ratio of 1:32 by the machine and filter it through a double ultrafiltration...

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Problems solved by technology

[0003] The above-mentioned hemodiafiltration method requires manual preparation, or on-line preparation of a hemofiltration machine to form a replacement fluid. The on-line preparation of a replacement fluid is formed by ultrafiltration of the dialysate from the dialysis area of ​​the hemofilter or bacterial filter into the blood area. Due to the need Only specialized equipment such as hemofiltration machines can be formed, and the cost of treatment is high

[0004] The hemodialysis machine (hemodialysis machine for short) in the prior art can only carry out hemodialysis, can not realize hemofiltration; When the blood flow is less than 100ml / min, the dialysis machine will alarm and interrupt the hemodialysis, which will bring inconvenience to the patient's blood purification

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