Antibacterial gel and preparation method thereof

A technology of gel and xanthan gum, applied in the field of medicine, can solve the problem of easy recurrence of drug resistance, and achieve the effects of good curative effect, good medication compliance, and promotion of bacteriostatic effect.

Inactive Publication Date: 2019-09-03
广州梅彭健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional western medicine gels are prone to drug resistance and relapse

Method used

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  • Antibacterial gel and preparation method thereof
  • Antibacterial gel and preparation method thereof
  • Antibacterial gel and preparation method thereof

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preparation example Construction

[0046] The present invention also provides a preparation method of antibacterial gel,

[0047] Including phase A, phase B, phase C and phase D, said phase A, phase B, phase C and phase D are:

[0048] Phase A:

[0049] Humectant 1-5%

[0050] Thickener 0.2-1%

[0051] Solvent 51-91%

[0052] Phase B:

[0053] Neutralizer 0.2-0.8%

[0054] Solvent 1-3%

[0055] Phase C:

[0056] Emulsifier 2.3-7%

[0057] Perilla seed oil 0.1-2%

[0058] Phase D:

[0059]

[0060]

[0061] Prepared by a method comprising the following steps:

[0062] (1) Mix the components of phase B to obtain pre-dispersed phase B; mix the components of phase C to obtain pre-dispersed phase C.

[0063] (2) Mix the water and glycerin of the components of phase A, and add acrylates / C10-30 alkanol acrylate crosslinked polymer and xanthan gum under homogeneous conditions to obtain phase A;

[0064] (3) Add pre-dispersed phase B to phase A, heat up to 80-90°C while stirring, and then homogenize; ...

Embodiment 1

[0073]

[0074] Preparation:

[0075] (1) Mix the components of phase B to obtain a pre-dispersed phase B; mix the components of phase C to obtain a pre-dispersed phase C.

[0076] (2) Add the deionized water and glycerin of phase A into the emulsification pot and mix, and under the condition of low-speed homogeneity (30 rpm), cross-link and polymerize the acrylates / C10-30 alkanol acrylate in phase A Carbopol Ultrez 21 Polymer) and xanthan gum were slowly sprinkled into the emulsification pot and homogenized for 3 minutes to obtain phase A.

[0077] (3) Add pre-dispersed phase B into phase A, heat up to 82-85°C while stirring, and homogenize at medium speed (60 rpm) for 4 minutes.

[0078] (4) Until it is fully dispersed, cool down to 60-65°C, add the pre-dispersed C phase components, stir well, and homogenize (2800 rpm) for 2 minutes;

[0079] (5) After homogenization, cool down to below 40°C, add phase D substances in turn, stir well, take samples, test, filter, and disch...

Embodiment 2

[0081]

[0082]

[0083] Preparation:

[0084] (1) Mix the components of phase B to obtain a pre-dispersed phase B; mix the components of phase C to obtain a pre-dispersed phase C.

[0085] (2) Add the deionized water and glycerin of phase A into the emulsification pot and mix them, and crosslink and polymerize the acrylates / C10-30 alkanol acrylate in phase A under the condition of low-speed homogeneity (25 rpm) (Carbopol Ultrez 21 Polymer) and xanthan gum were slowly sprinkled into the emulsification pot, and homogenized for 2 minutes to obtain phase A.

[0086] (3) Add pre-dispersed phase B into phase A, heat up to 82-85°C while stirring, and homogenize at a medium speed (60 rpm) for 5 minutes.

[0087] (4) Until it is fully dispersed, cool down to 60-65°C, add the pre-dispersed C phase components, stir well, and homogenize (2800 rpm) for 3 minutes;

[0088] (5) Cool down to below 40°C, add phase D substances in turn, stir well, take samples, test, filter, discharge ...

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Abstract

The invention relates to an antibacterial gel and a preparation method thereof, the antibacterial gel is prepared by the following raw materials by weight percentage: 1-5% of a humectant, 0.21-1% of athickener, 54-92% of a solvent, 0.2-0.8% of a neutralizer, 2.3-7% of an emulsifier, 0.1-2% of perilla seed oil, 0.5-5% of a medicinal rhubarb extract, 0.2-3% of a coptis root extract, 0.8-3% of a gentian root extract, 0.5-2% of a peony root extract, 0.3-3% of a Centella asiatica extract, 0.3-3% of a grape seed extract, 0.3-3% of a scutellaria root extract, 0.3-2% of a honeysuckle flower extract,0.3-4% of a rosemary leaf extract, and 0.3-3% of an aloe extract. The antibacterial gel of the invention has clear and transparent performance, uniform and fine performance, and excellent stability, and has good antibacterial effect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an antibacterial gel and a preparation method thereof. Background technique [0002] Gynecological inflammation is a common disease in gynecology, mainly divided into bacterial vaginosis, fungal vaginitis, non-specific vaginitis and trichomonal vaginitis. According to the incomplete statistics of the World Health Organization, the incidence rate of various gynecological diseases in women is more than 65%, and it shows a younger trend, becoming one of the main diseases that threaten the health of women in our past. The methods for treating gynecological inflammation include physical therapy and drug therapy. Physiotherapy can cause the destruction of epithelial cells; drug therapy is mainly based on local treatment, because the vagina is rich in capillaries and lymphatic vessels, and the vagina has no clear nerve endings, the patient's pain stimulation is small when administerin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/886A61K9/06A61K47/32A61K47/36A61K47/22A61K47/26A61P15/02
CPCA61K9/0034A61K9/06A61K36/23A61K36/355A61K36/515A61K36/53A61K36/535A61K36/539A61K36/65A61K36/708A61K36/71A61K36/718A61K36/87A61K36/886A61K36/896A61K47/22A61K47/26A61K47/32A61K47/36A61P15/02A61K2300/00
Inventor 刘芸柳峰
Owner 广州梅彭健康科技有限公司
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