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Preparation method of porous material enhanced bletilla striata dressing

A porous material, Bletilla striata technology, applied in the field of biomedicine, can solve the problems that Bletilla striata dressing is difficult to apply to the wound at one time, cannot be well applied to the wound, and limits the application range of the dressing, so as to achieve rapid healing, soft texture, The effect of good biocompatibility

Active Publication Date: 2019-09-06
WUHAN TEXTILE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But because the bletilla striata polysaccharide is very soluble in water, it is easy to adhere and difficult to detach during operation, so it cannot be well attached to the wound during use.
[0004] The existing Bletilla striata dressing will dissolve and stick due to the blood on the gloves worn by doctors during surgical operations, making it difficult for the Bletilla striata dressing to be applied to the wound at one time
The operating layer of traditional multi-layer dressings is non-degradable, which greatly limits the application range of dressings

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0025] A kind of porous material strengthens the preparation method of bletilla striata base dressing, described preparation method is carried out according to the following steps:

[0026] a Preparation of Bletilla striata polysaccharide casting solution

[0027] The bletilla striata polysaccharide solution is prepared by dissolving the bletilla striata polysaccharide in water to prepare a bletilla striata polysaccharide solution with a mass fraction of 3-10%, and placed in a vacuum state with a vacuum degree of 0.1-0.5 MPa to remove air bubbles to obtain a bletilla striata polysaccharide casting solution for future use.

[0028] b. Preparation of bletilla striata polysaccharide solution

[0029] The bletilla striata polysaccharide solution is prepared by dissolving the bletilla striata polysaccharide in water to prepare a bletilla striata polysaccharide solution with a mass fraction of 10-15%, and placed in a vacuum state with a vacuum degree of 0.1-0.5 MPa to remove air bub...

Embodiment 1

[0037] a Preparation of Bletilla striata polysaccharide casting solution

[0038] The Bletilla striata polysaccharide is dissolved in water to prepare a Bletilla striata polysaccharide solution with a mass fraction of 3%, and the Bletilla striata polysaccharide solution is placed in a vacuum state with a vacuum degree of 0.1 MPa to remove air bubbles to obtain a Bletilla striata polysaccharide film casting solution for use.

[0039] b Preparation of Bletilla striata polysaccharide solution

[0040] The Bletilla striata polysaccharide was dissolved in water to prepare a Bletilla striata polysaccharide solution with a mass fraction of 10%, and the Bletilla striata polysaccharide solution was obtained in a vacuum state with a vacuum degree of 0.1 MPa to remove air bubbles.

[0041] c Preparation of Porous Material Reinforced Bletilla striata Dressing

[0042] The Bletilla striata polysaccharide film casting liquid prepared in step a is poured into the groove of the flat mold, an...

Embodiment 2

[0046] a Preparation of Bletilla striata polysaccharide casting solution

[0047] The Bletilla striata polysaccharide is dissolved in water to prepare a Bletilla striata polysaccharide solution with a mass fraction of 5%, and the Bletilla striata polysaccharide solution is placed in a vacuum state with a vacuum degree of 0.2 MPa to remove air bubbles to obtain a Bletilla striata polysaccharide film casting solution for use.

[0048] b Preparation of Bletilla striata polysaccharide solution

[0049] The Bletilla striata polysaccharide was dissolved in water to prepare a Bletilla striata polysaccharide solution with a mass fraction of 13%, and the Bletilla striata polysaccharide solution was obtained by placing it in a vacuum state with a vacuum degree of 0.3 MPa to remove air bubbles.

[0050] c Preparation of Porous Material Reinforced Bletilla striata Dressing

[0051] The Bletilla striata polysaccharide film casting liquid prepared in step a is poured into the groove of the...

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PUM

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Abstract

The invention relates to a preparation method of a porous material enhanced bletilla striata dressing, and belongs to the technical field of biological medicines. According to the preparation method,part of bletilla striata polysaccharide casting solution is frozen in an orienteering manner, connecting layer bletilla striata polysaccharide solution is poured on the upper portion of bletilla striata polysaccharide casting solution without being incompletely frozen, a gelatin sponge or medical oxidized cellulose gauze difficult to being solved into water is laid on the upper portion of fused solution, porous materials, the connecting layer bletilla striata polysaccharide solution and the bletilla striata polysaccharide casting solution are integrally frozen under the action of a metal conductor, and the porous material enhanced bletilla striata dressing is acquired by the aid of a freeze drying technique. The method solves the problems that an existing bletilla striata dressing is easily dissolved in water and difficultly pasted on a wound in the clinical medical process. According to the preparation method, used materials are degradable and absorbed, and damage of the used materials to human bodies is omitted. According to the preparation method, mechanical property and operating performance of the bletilla striata dressing are enhanced, so that the bletilla striata dressing ispopularized in the field of surgical operation, wound repairing, tissue engineering and the like.

Description

technical field [0001] The invention relates to a preparation method of porous material reinforced bletilla striata dressing, which belongs to the technical field of biomedicine. Background technique [0002] In the clinical use of surgery, the rapid hemostasis of the wound has an important impact on the postoperative recovery of patients. Bletilla striata polysaccharide has the functions of antibacterial and anti-inflammatory, removing putrefaction and promoting granulation, astringent sores, etc., and has no toxic and side effects, is safe and comfortable, degradable, non-polluting, and has good biocompatibility. It is a good natural bioengineering material and can be used as a drug dressing in pharmaceutical preparations. [0003] The Chinese patent publication number is CN102477102A, the publication date is May 12, 2012, and the title of the invention is a method for using bletilla striata polysaccharides as a hemostatic material. The invention uses bletilla striata pol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/32A61L15/42A61L15/44A61L15/46A61L15/62
CPCA61L15/28A61L15/32A61L15/42A61L15/425A61L15/44A61L15/46A61L15/62A61L2300/232A61L2300/404A61L2300/41A61L2300/412A61L2400/04C08L89/00C08L1/04
Inventor 杨红军王晗许愿刘昌俊张骞陈欣庄燕徐卫林
Owner WUHAN TEXTILE UNIV
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