Occlusion device and preparation method thereof

Abstract

The invention discloses an occlusion device and a preparation method thereof. The occlusion device comprises a framework and flow choking membranes, wherein the framework comprises a waist and barbs connected with at least one end of the waist, the flow choking membranes are fixed on at least one end of the waist and / or on the inner sides of the barbs, a cavity is formed between the framework andthe flow choking membranes, and the framework or the flow choking membranes are provided with injection holes. The provided occlusion device has the advantages that the adopted structure makes the occlusion device have a smaller size, the occlusion device can be used in a transport sheath with a smaller diameter, has less damage to the blood vessel wall, is also suitable for interventional occlusion of younger people, reduces the use amount of the material, reduces the complication rate after implantation, and also reduces the cost; with the help of the swelling properties of the solid xerogelafter being in contact with the blood, the occlusion device can fill the defects of the tissue of the irregular shape, be applied to the situations that the edge of a defect part is narrower and theshape of the defect part is complex, and broaden the application range of interventional therapy of the cardiac septal defect.

Description

technical field [0001] The invention relates to a medical occlusion device and a preparation method thereof, in particular to a self-expandable cardiac septal defect occlusion device and a preparation method thereof. Background technique [0002] With the continuous development of implantable medical devices and interventional cardiology, transcatheter percutaneous occluder treatment of atrial septal defect (ASD), patent foramen ovale (PFO), ventricular septal defect (VSD) and arterial Cardiac catheterization (PDA) is becoming an increasingly important and widely accepted approach. [0003] With regard to the research on occluders, rich experience has been accumulated in both scientific research and clinical fields, especially nickel-titanium alloy occluders, which have been clinically used for more than ten years. The nickel-titanium alloy cardiac septal occluder has good elastic memory, After being inserted into the human body, it can immediately return to the required st...

AI Technical Summary

Problems solved by technology

However, these occluders also have some problems. For example, due to the large double-disc surface, it is required that the edge of the defect site has a certain distance from the coronary sinus, superior vena cava, inferior vena cava, pulmonary vein, and atrioventricular valve. Only the space opened by the occluder can meet the basic requirements of interventional occluder therapy, which makes some patients unable to use interventional therapy; in addition, these occluders have a large structure and a large amount of materials, whether it is nickel-titanium alloy or Degradable materials have a greater impact on later complications, and a larger delivery catheter is required during the delivery process, causing greater damage to blood vessels; and the shape of the defect site is different in different patients, and it is best to insert a fixed-shaped seal If the occluder is used, it will not be able to completely occlude the defect, and there will be problems such as large residual shunt

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