Mild-hypothermia protection rat radiation-induced pulmonary injury gene screening and path analyzing method

A technique for radiation-induced lung injury, analytical methods, applied in the field of radiation protection
CN110452960APending Publication Date: 2019-11-15CHINA INST FOR RADIATION PROTECTION
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHINA INST FOR RADIATION PROTECTION
Publication Date
2019-11-15

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Abstract

The invention belongs to the technical field of radiation protection, and relates to a mild-hypothermia protection rat radiation-induced pulmonary injury gene screening and path analyzing method. Themethod includes the following steps of firstly, conducting mild-hypothermia intervention treatment on an established rat radiation-induced pulmonary injury model; secondly, screening out a differential expression gene of the mild-hypothermia treatment radiation-induced pulmonary injury after treatment, and conducting enrichment analysis on the functions of the gene; thirdly, selecting a differential expression remarkable gene after analysis for result verification. By means of the mild-hypothermia protection rat radiation-induced pulmonary injury gene screening and path analyzing method, the mild-hypothermia protection rat radiation-induced pulmonary injury related gene can be screened out, the function and path enrichment analysis is conducted on the differential expression gene, and theexplanation on the gene level is provided for the mild-hypothermia protection rat radiation-induced pulmonary injury.
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Description

technical field

[0001] The invention belongs to the technical field of radiation protection, and relates to a gene screening and pathway analysis method for mild hypothermia protection against radiation-induced lung injury in rats. Background technique

[0002] The national cancer statistics report for many years has pointed out that: lung cancer continues to be the first in the incidence and mortality of cancer in my country, and breast cancer has the highest incidence rate among female cancers, and the most common part of cancer is still located in the chest.

[0003] In the case of continued high incidence of cancer, multimodal diagnosis and treatment methods for patients with primary chest tumors and metastatic tumors have greatly improved the survival rate and prolonged the survival time of patients, especially radiotherapy, which has become one of the main treatment methods for cancer patients . However, while radiotherapy kills tumor cells, it will also cause damage ...

Claims

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