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Durable enhanced implant having three-leaf bioprosthetic valve and preparation method of durable enhanced implant having three-leaf bioprosthetic valve

An enhanced and grafted technology, applied in the field of medical devices, can solve the problems that the durability of aortic valve stents cannot meet the survival needs of the population, and achieve the effects of meeting the needs of an aging society, high durability, and reducing treatment costs

Active Publication Date: 2019-12-06
SHANGHAI CHANGHAI HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as our country enters an aging society, for example, the average life expectancy of the population in Shanghai is as high as 82 years old, and the age requirement for this type of surgery is ≥70 years old, so the durability of the existing aortic valve stents is far from meeting the survival needs of the population

Method used

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  • Durable enhanced implant having three-leaf bioprosthetic valve and preparation method of durable enhanced implant having three-leaf bioprosthetic valve
  • Durable enhanced implant having three-leaf bioprosthetic valve and preparation method of durable enhanced implant having three-leaf bioprosthetic valve
  • Durable enhanced implant having three-leaf bioprosthetic valve and preparation method of durable enhanced implant having three-leaf bioprosthetic valve

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Experimental program
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Effect test

Embodiment 1

[0028] This embodiment provides a durability-enhanced trilobate bioprosthetic graft and a preparation method thereof.

[0029] figure 1 It is a structural schematic diagram of a durability-enhanced three-leaflet bioprosthetic graft in Example 1 of the present invention.

[0030] Such as figure 1 As shown, the durability-enhanced three-leaflet bioprosthesis graft 100 in this embodiment includes a graft body 10 , a membrane 20 and a three-leaflet bioprosthesis body 30 .

[0031] figure 2 It is a structural schematic diagram of the graft main body in Embodiment 1 of the present invention.

[0032] Such as figure 2As shown, the graft main body 10 is a titanium alloy (not limited to metal and proportion), laser engraved, and a cylindrical stent skeleton composed of a plurality of continuous sine wave stent rings. Titanium alloy has memory performance, laser engraving operation is precise, and the mechanical properties of continuous sine wave structure are very reliable. The...

Embodiment 2

[0069] The durability-enhanced three-leaflet bioprosthesis graft in the second embodiment also includes a graft body, a covering membrane, and a three-leaf bioprosthesis body. The only difference between the durability-enhanced three-leaflet biological valve graft in this embodiment and the durability-enhanced three-leaflet biological valve graft 100 in Embodiment 1 is that the structure of the main body of the graft is different. The materials of the bioprosthesis are different, the sutures used for suturing are different, and other structures such as the membrane and the three-leaf bioprosthesis are the same in these two embodiments.

[0070] Figure 7 It is a structural schematic diagram of the main body of the graft in the second embodiment of the present invention.

[0071] Such as Figure 7 As shown, the main body of the graft in this embodiment is made of stainless steel or nickel alloy (not limited to the metal and proportion), laser-engraved, and a stent skeleton co...

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Abstract

The invention provides a durable enhanced implant having three-leaf bioprosthetic valve. The durable enhanced implant having three-leaf bioprosthetic valve is characterized by comprising an implant main body, an overlay film and the three-leaf bioprosthetic valve body, wherein the overlay film coats the outside of the implant main body; the three-leaf bioprosthetic valve body is arranged in the implant main body, is provided with three valve leaflets and two reinforced protruding parts, each valve leaflet is provided with a valve leaflet main body and a reinforced suture part, each valve leaflet main body is in the shape like a semiellipse, and is provided with a large curve edge, a small curve edge, and a first end and a second end located at connecting positions of the large curve edge and the small curve edge, each first end and the corresponding second end of the adjacent valve leaflet main body are in overlapping suture together, and each reinforced suture part is in overlapping suture on the corresponding large curve edge and is sutured to a bracket framework and the overlay film; the two reinforced protruding parts are respectively connected to the ends of the adjacent largecurve edges of the outmost-side two valve leaflets, and the two reinforced protruding parts are mutually overlapped to be sutured on the bracket framework and the overlay film; and the three valve leaflet main bodies and the two reinforced protruding parts are in integrated cutting.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a durability-enhanced three-leaf biological valve graft and a preparation method thereof. Background technique [0002] Valvular heart disease is a group of diseases characterized by structural damage, fibrosis, adhesion, shortening, myxomatous degeneration, ischemic necrosis, calcinosis, or congenital malformation of heart valves (including leaflets, chordae, and papillary muscles). disease. Aortic valve degenerative stenosis is the most common primary degenerative valvular disease. The disease has a high incidence, insidious onset, rapid progression, and extremely poor prognosis. Among people over 75 years old, the incidence of aortic valve stenosis was 4.6%, and the incidence of moderate to severe stenosis was as high as 2.8%. There are no obvious clinical manifestations in the early stage of the disease. However, in the advanced stage of the disease, once symptoms appear, th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/24
CPCA61F2/2412A61F2/2415A61F2/2418A61F2220/0075A61F2240/001
Inventor 景在平李逸明鲍贤豪冯家烜左辉周建冯睿赵志青李涛赵玉玺何潇敏雷忠卫
Owner SHANGHAI CHANGHAI HOSPITAL
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