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Fractional flow reserve simulation parameter customization, calibration and/or training

A simulator, segmenter technology, applied in the field of imaging

Pending Publication Date: 2019-12-13
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

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  • Fractional flow reserve simulation parameter customization, calibration and/or training
  • Fractional flow reserve simulation parameter customization, calibration and/or training
  • Fractional flow reserve simulation parameter customization, calibration and/or training

Examples

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Embodiment Construction

[0018] figure 1 A system 100 including an imaging system 102 (eg, a CT scanner) is schematically shown. In a variation, system 100 includes an x-ray imager. The imaging system 102 includes a body-fixed gantry 104 and a rotating gantry 106 , which is rotatably supported by the fixed gantry 104 and rotates about an examination region 108 about a z-axis. A subject support 110 , such as a couch, supports a target or object in the examination area 108 .

[0019] A radiation source 112 , such as an X-ray tube, is rotatably supported by the rotating gantry 106 , rotates with the rotating gantry 106 , and emits radiation through the examination region 108 . Radiation sensitive detector array 114 subtends an angular arc opposite radiation source 112 across examination region 1088 . The radiation sensitive detector array 114 detects radiation passing through the examination region 108 and generates electrical signal(s) (projection data) indicative thereof. A reconstructor 116 recons...

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Abstract

A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including a including a biophysical simulator (126) with a segmentor (202) and aboundary condition determiner (206). The computing system further includes a processor (120) configured to execute the biophysical simulator to compute a fractional flow reserve index with cardiac imaging data and at least one of an adapted coronary tree segmentation and an adapted boundary condition.

Description

technical field [0001] The following generally relates to imaging, and more specifically to the customization, calibration and / or training of fractional flow reserve simulation (FFR), and is described for and applicable to the specific application of FFR-computed tomography (FFR-CT) in X-ray FFR. Background technique [0002] Fractional flow reserve (FFR) is an invasive measurement in the Cath Lab that quantifies the hemodynamic significance of coronary artery lesions due to calcification or soft plaque by the FFR index. This index indicates the functional severity of the coronary stent, which is calculated from pressure measurements taken during coronary angiography and is defined as the distal blood pressure (behind the stenosis) compared to the proximal blood pressure (near the porta) under hyperemic conditions . That is, the FFR index expresses the maximum flow down the vessel in the presence of a stent compared to the maximum flow assuming no stenosis. The FFR value ...

Claims

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Application Information

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IPC IPC(8): G16H50/30G16H50/50
CPCG16H50/30G16H50/50G06T7/10G16H10/60A61B5/0044A61B5/14535A61B5/7475G06T7/0014G06T2207/20081G06T2207/30048
Inventor H·尼克基施H·施米特
Owner KONINKLJIJKE PHILIPS NV