Preparation method of high-purity L-PFOS and high-purity L-PFOS

Abstract

Relating to the technical field of chemical products, the invention provides a preparation method of high-purity L-PFOS (L-perfluorooctane sulfonic acid). The method includes a separation stage and aconcentration drying stage, the separation stage comprises: step 1, selecting solid PFOS to prepare a PFOS methanol solution, which has a concentration of 5mg / mL-15mg / mL; and step 2, subjecting the PFOS methanol solution to semi-preparative liquid chromatography-evaporative light scattering separation so as to collect L-PFOS; and the concentrating and drying stage comprises the following steps: concentrating and drying; and the concentration drying stage include: step 3, subjecting the L-PFOS collection liquid collected in step 2 to concentration drying treatment so as to obtain L-PFOS. The method provided by the invention is a rapid and accurate preparation method of the high-purity L-PFOS, can improve the accuracy of the preparation process, ensure the experiment success, improve the experiment efficiency and meet the requirement of accurate detection, and has important research significance.

Description

Technical field [0001] The invention relates to the technical field of chemical products, in particular to a method for preparing high-purity L-PFOS and high-purity L-PFOS. Background technique [0002] As one of the most important chemical products in the 20th century, fluorinated organic compounds have a wide range of applications in industrial production and daily consumption. Perfluorooctane sulfonic acid (PFOS) and its salts are the most important type of fluorinated organic compounds. With its stable properties and the advantages of oleophobicity and hydrophobicity, PFOS is widely used as an antifouling agent on the surface of textiles and leather products; used in the production of coatings, foam fire extinguishing agents and pesticides; used in adhesives, pharmaceutical products, Flame retardants, petroleum and mining products, and even used in paper food packaging materials and non-stick pans. However, PFOS is currently one of the most difficult-to-degrade organic poll...

AI Technical Summary

Problems solved by technology

As time goes on, this distribution difference gradually becomes larger, so it is more difficult to study

[0005]Second, the separation and detection of PFOS isomers are difficult

The number of PFOS isomers is large, and they are hydrophobic and oleophobic, and have no response on detectors such as ultraviolet and diode arrays, which makes the separation and detection of PFOS isomers difficult.

Spectroscopy can detect the total amount of PFOS, but cannot distinguish isomers

The combination of chromatographic technology with a variety of detectors and the rapid development of new separation materials have made significant progress in the separation and detection of PFOS isomers, but the number of PFOS isomers that can be detected is not the same as the theoretical value. There is still a big gap than

[0006] At present, there are few reports on the research of L-PFOS and B-PFOS in my country, the preparation method of PFOS isomer monomer has not been reported, and the relevant standard materials are also not listed

Images