Lactobacillus plantarum for relieving mental stress and application thereof

A technology of Lactobacillus plantarum and mental stress, applied in the field of microbiology, can solve problems affecting learning, memory and cognitive ability, intervention measures that are not worth the effort, and impaired gastrointestinal function

Pending Publication Date: 2020-01-14
BEIJING SCITOP BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Eventually, it will cause an increase in negative emotions such as anxiety, and it will also affect learning, memory and cognitive abilities, and even lead to damage to gastrointestinal function, which will negatively affect systemic functions
Until now, treatments for emotional problems caused by stress have revolved around medications, and the side effects of these medications make these interventions more than worthwhile

Method used

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  • Lactobacillus plantarum for relieving mental stress and application thereof
  • Lactobacillus plantarum for relieving mental stress and application thereof
  • Lactobacillus plantarum for relieving mental stress and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0025] Example: Effect of Lactobacillus plantarum P-8 on alleviating mental stress in human body.

[0026] 1 Experimental method

[0027] 1.1 Experimental strain preparation

[0028] Lactobacillus plantarum P-8 powder preparation, live bacteria content 2×10 10 CFU / pack (2g / pack). The test group consisted of Lactobacillus plantarum P-8 and maltodextrin, and the placebo group only contained maltodextrin. The above materials were provided by Beijing Ketuo Hengtong Biotechnology Co., Ltd.

[0029] 1.2 Experimental design

[0030] Using random, double-blind, placebo-controlled methods, 103 adults aged 18-60 were divided into an experimental group and a placebo group (52 people in the experimental group took 1 packet of Lactobacillus plantarum P-8 every day ( 2g / bag); 51 people in the placebo group took 1 bag of placebo (2g / bag) every day). A 12-week clinical trial was conducted to study the effects on the mental state, memory and cognitive abilities of a population. All sub...

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PUM

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Abstract

The present application discloses a strain of lactobacillus plantarum for relieving mental stress and an application thereof. Unhealthy emotions and mental states such as stress, anxiety and depression can increase intestinal permeability and reduce immunity of a body. Both of the factors cause change on microbial populations, and result in microbial displacement due to weakened intestinal immuneprotection. Clinical studies show that the lactobacillus plantarum P-8 relieves stress and anxiety in stressed people by regulating metabolic pathways and anti-inflammatory properties.

Description

technical field [0001] The application relates to the technical field of microorganisms, in particular to a strain of Lactobacillus plantarum for relieving mental stress and its application. Background technique [0002] The fast-paced life in modern society has caused our nerves to be in a state of tension almost all the time, and an opportunity may trigger acute anxiety. According to the latest data from WHO, at least 300 million people around the world are troubled by stress and anxiety, and the number of suicides caused by emotions exceeds 800,000 every year. Stress increases glucocorticoid levels and affects the hypothalamic-pituitary-adrenal axis, which in turn negatively affects the immune system and leads to changes in neuronal morphology and even neuronal cell death. It will eventually cause an increase in negative emotions such as anxiety, and it will also affect learning, memory and cognitive abilities, and even cause damage to gastrointestinal function, which wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K35/747A61P25/22A61P25/24A61P25/00A23L33/135C12R1/25
CPCA61K35/747A61P25/22A61P25/24A61P25/00A23L33/135A23V2002/00C12R2001/25C12N1/205A23V2400/169A23V2200/322
Inventor 张建军马杰杨慧娟张凌宇刘晓军
Owner BEIJING SCITOP BIO TECH CO LTD
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