A kind of traditional Chinese medicine composition and application for treating Hashimoto's thyroiditis

A thyroiditis, Hashimoto's technology, applied in the field of medicine, can solve problems such as the physical and mental impact of patients, the advent of Chinese patent medicine, etc., and achieve the effect of improving the level of thyroid inflammation

Active Publication Date: 2021-09-17
CHIATAI QINGCHUNBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine can only use hormone therapy, and the adverse reactions of hormones often have a huge impact on the patient's body and mind
[0007] Although Chinese medicine has a certain understanding of HT, and a certain number of proven prescriptions have been applied clinically, there is no Chinese patent medicine for this disease.

Method used

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  • A kind of traditional Chinese medicine composition and application for treating Hashimoto's thyroiditis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh raw materials: Codonopsis 1000g, Scutellaria baicalensis 500g, bergamot 200g, tangerine peel 100g, add 10 times the amount of water to the raw materials, heat and reflux to extract twice, each time for 2 hours, filter the extract, combine and concentrate to 1800ml, then add After 3.6ml of sorbitol, mix well to make a mixture.

Embodiment 2

[0039] Weigh raw materials: Codonopsis 500g, Astragalus 500g, Prunella vulgaris 300g, tangerine peel 200g, add 10 times the amount of water to the raw materials, heat and reflux to extract twice, each time for 2 hours, filter the extract, combine and concentrate to extract, Adopt boiling granulation equipment, add dextrin 250g, make granule.

Embodiment 3

[0041]Weigh raw materials: Codonopsis 800g, Scutellaria baicalensis 200g, Prunella vulgaris 200g, Tangerine peel 200g, add 10 times the amount of water to the raw materials, heat and reflux to extract twice, each time for 2 hours, filter the extract, concentrate and condense to extract Add 150g of dextrin and 100g of starch, after mixing, adopt boiling granulation equipment to make granules, and adopt capsule filling equipment to fill capsules to make capsules.

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Abstract

The invention provides a traditional Chinese medicine composition for treating Hashimoto's thyroiditis and its application. The traditional Chinese medicine composition is composed of Chinese medicinal materials for invigorating the middle and nourishing qi, Chinese medicinal materials for clearing the liver and purging fire, and Chinese medicinal materials for soothing the liver and regulating qi. The mass ratio of liver-regulating qi-related Chinese medicinal materials is 2-10:1-5:1-3. The present invention also provides the application of the traditional Chinese medicine composition in the preparation of medicine for treating Hashimoto's thyroiditis. The traditional Chinese medicine composition of the invention can significantly improve the thyroid inflammation level, the overall immune activation level, and the overall inflammatory response level of EAT rats, and can be used for the treatment of Hashimoto's thyroiditis. The traditional Chinese medicine composition of the invention makes the efficacy of each medicine synergistic, and it can be prepared into a traditional Chinese medicine preparation, thereby effectively treating Hashimoto's thyroiditis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition for treating Hashimoto's thyroiditis and its application. Background technique [0002] Hashimoto's thyroiditis (Hashimoto's thyroiditis, HT), also known as chronic lymphocytic thyroiditis, lymphatic goiter, is a common thyroid autoimmune disease, and its pathological feature is diffuse infiltration of lymphocytes and plasma cells in the thyroid gland. Destruction of thyroid follicles, giant eosinophils, and new capillaries in glandular tissue can eventually lead to hypothyroidism, which is clinically manifested as euthyroid, hyperthyroidism, or hypothyroidism. [0003] HT is very common clinically, mostly in middle-aged people, but any age group can be involved. It is highly prevalent in some areas of my country, with an overall incidence ranging from 0.3% to 10%, and female patients are 5 to 10 times that of male patients...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P5/14
CPCA61K36/344A61K36/481A61K36/536A61K36/539A61K36/752A61P5/14A61K2300/00
Inventor 张继全王源冯怡王优杰张卓钰
Owner CHIATAI QINGCHUNBAO PHARMA
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