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Integrated micro-molding gradient degradation woven artificial ligament and preparation method thereof

A technology of artificial ligaments and degradation machines, applied in ligaments, prostheses, medical science, etc., to achieve good wear resistance and fatigue performance, avoid secondary processing, dense pore structure, and stable structure

Active Publication Date: 2020-02-07
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to prepare a gradient degradable woven artificial ligament, which can be integrally micro-formed, has a simple manufacturing method, adjustable structural parameters, and has excellent mechanical properties and gradient degradation properties

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Integrated micro-molding gradient degradation woven artificial ligament and preparation method thereof
  • Integrated micro-molding gradient degradation woven artificial ligament and preparation method thereof
  • Integrated micro-molding gradient degradation woven artificial ligament and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0040] A preparation method of an integrated micro-molding gradient degradation woven artificial ligament:

[0041] The first step is to determine the weave diagram of the multi-layer fabric. The fabric weave is twill; the twill weave is used as the double-layer surface weave, and the double-layer weave structure diagram is obtained by means of tubular jointing and compounding. The jointing method is the top joint and bottom joint method, and the number of joints is 16 per cycle;

[0042] The second step is to determine the map on the machine. Warp density: 500 pcs / 10cm, weft density: 50 pcs / 10cm, the way of drawing in healds is straight threading method, the number of threads per reed: 4 pcs / reed, reed number 200.

[0043] The third step is to weave on the machine. The yarns used in surface warp 31 and surface weft 41 are 0.2mm PGLA monofilament, and the yarns used in inner warp 32 and inner weft 42 are 0.2mm PPDO monofilament. Surface warp: inside warp = 1:1, surface weft...

Embodiment 2

[0048] A preparation method of an integrated micro-molding gradient degradation woven artificial ligament:

[0049] The first step is to determine the weave diagram of the multi-layer fabric. The fabric weave is plain weave; the plain weave weave is used as the double-layer surface weave, and the double-layer weave structure diagram is obtained by lamellar jointing and compounding. The jointing method is the bottom joint method, and the number of joints is 32 per cycle; Using this two-layer organizational chart as the lower-level organizational chart, a four-layer organizational chart is obtained by sheet-like jointing and compounding. The jointing method is the bottom joint method, and the number of joints is 32 per cycle.

[0050] The second step is to determine the map on the machine. Warp density: 1200 strands / 10cm, weft density: 150 strands / 10cm, the way of drawing in healds is the straight-through method, the number of penetrations per reed: 8 strands / reed, and the numb...

Embodiment 3

[0055] A preparation method of an integrated micro-molding gradient degradation woven artificial ligament:

[0056] The first step is to determine the weave diagram of the multi-layer fabric. The fabric weave is plain weave; use the plain weave weave as a double-layer surface weave, and obtain a double-layer weave structure diagram in a sheet-like jointing and compounding method. The jointing method is the bottom joint method, and the number of joints is 64 per cycle; Using the weave diagram as the basic weave, the method of tying is the up-and-down method. Repeat the above steps 3 times to obtain a 10-layer fabric weave.

[0057] The second step is to determine the map on the machine. Warp density: 2000 threads / 10cm, weft density: 300 threads / 10cm, the drawing method is partition threading method, the number of threads per reed: 16 threads / reed, and the number of reeds is 200.

[0058] The third step is to weave on the machine. 1. The yarn used for surface warp and weft of...

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Abstract

The invention discloses an integrated micro-molding gradient degradation woven artificial ligament. The integrated micro-molding gradient degradation woven artificial ligament is characterized in thatthe artificial ligament is of an integrally molded structure and is a three-section type woven artificial ligament provided with thighbone and shinbone bone tunnel sections at the two ends and provided with a joint cavity free section in the middle, wherein the thighbone and shinbone bone tunnel sections are constituted by 2-10 layers of tubular or sheet-like jointing tissue; the thighbone and shinbone bone tunnel sections are each of an interwoven structure constituted by multiple layers of warp yarn and weft yarn, and all the layers are connected through the jointing tissue; and parallellyarrayed warp yarn serves as the joint cavity free section. The preparation method comprises the steps of determining of an organization chart of a multi-layer fabric, determining of a looming draft, looming weaving, post-processing and the like. Based on regulation and control over weaving parameters and arrangement of the yarn with different degradation characteristics, gradient degradation of the ligament is achieved, the stress shielding effect at the later stage of implantation is reduced, and a three-dimensional topological structure of the artificial ligament synergistically responds with the biomechanical property, degradation property and tissue induction property of the artificial ligament.

Description

technical field [0001] The invention relates to an integrated micro-molding gradient degradation woven artificial ligament and a preparation method thereof, belonging to the technical field of artificial ligaments. Background technique [0002] The anterior cruciate ligament (ACL) is one of the four main ligaments in the human knee joint. It is surrounded by synovial tissue, connects the femur and tibia, and maintains the stability of the knee joint by limiting the mobility of the joint. ACL injuries are often the result of complex and sudden stresses during everyday activities and sports. ACL is a dense connective tissue with limited vascularization and cannot heal itself after injury. Clinically, reconstructive surgery is mainly used to restore the stability of the knee joint. Autograft is still the "gold standard" in ACL reconstruction in clinic, but there are many donor site complications in autograft. The artificial ligament is easy to obtain, has no donor site compli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/08
CPCA61F2/08A61F2240/001
Inventor 林婧谢晓静王璐王富军关国平李超婧卢俊
Owner DONGHUA UNIV
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