Application of chelerythrine to preparation of medicine for inhibiting blastomyces albicans and staphylococcus aureus bi-species biofilm
A technology of Candida albicans and chelerythrine, which is applied in the directions of antibacterial drugs, antifungal agents, pharmaceutical formulations, etc., can solve the problems that have not yet been seen.
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[0021] The present invention will be described in further detail below in conjunction with the examples. The examples are only used to explain the content of the present invention, not to limit the present invention.
[0022] 1. Materials
[0023] 1.1 Experimental strains
[0024] Candida albicans SC5314 was purchased from the American Type Culture Collection;
[0025] Staphylococcus aureus ATCC25923 was purchased from the American Type Culture Collection.
[0026] 1.2 Reagents
[0027] Dimethyl sulfoxide DMSO was purchased from Shanghai Sigma-Aldrich Trading Co., Ltd.;
[0028] Normal saline was purchased from Shanghai Sigma-Aldrich Trading Co., Ltd.;
[0029] Methanol was purchased from Shanghai Sigma-Aldrich Trading Co., Ltd.;
[0030] Yeast extract powder was purchased from Shanghai Sigma-Aldrich Trading Co., Ltd.;
[0031] Glucose was purchased from Shanghai Sigma-Aldrich Trading Co., Ltd.;
[0032] Peptone was purchased from Shanghai Sigma-Aldrich Trading Co., Lt...
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