Portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method

Abstract

The invention discloses a portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method. The method is characterized in that a measurement system is constructed by adopting a portable nuclear magnetic resonance system, a mechanical vibration excitation device and a control console construction system, wherein the portable nuclear magnetic resonance system mainly comprises a nuclear magnetic resonance (NMR) frequency spectrometer, a power amplifier, a preamplifier, a transceiving switching module, a portable magnet module and a probe. When acting on a human body, the portable nuclear magnetic resonance system has no damage to organs and tissues, has no wound, and realizes safe, accurate, quantitative and non-invasive organ elasticity detection. The system is simple, scientific and reasonable, and the equipment is simple and optimized, has light weight and small volume, and is convenient to carry. The equipment is operated by one key, has no dependence on an operator and has high repeatability. The method is widely applicable to bedside testing and rapid screening, imaging is not needed, and measuring time is short. Motion sensitive gradient has certain motion frequency selectivity, and a measuring process is not easily influenced by motion and has high accuracy, and the defects of the prior art are overcome.

Description

technical field [0001] The invention relates to the technical field of nuclear magnetic resonance medical detection, in particular to a portable noninvasive quantitative detection method of nuclear magnetic resonance organ elasticity. Background technique [0002] Elasticity is an important mechanical parameter of biological tissue, which characterizes the difficulty of tissue deformation under the action of mechanical external force. Changes in tissue elasticity are closely related to its physiological and pathological state, and thus normal and pathological tissues can be distinguished. At present, detection methods based on tissue elasticity have been actively applied in tumor diagnosis, grading and rehabilitation evaluation of liver fibrosis. In traditional medicine, doctors qualitatively judge tissue elasticity through palpation, and then diagnose lesions. The diagnostic results have large errors and are greatly affected by the operator's subjective influence. In rece...

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method, which reasonably and effectively solves the problem that the ultrasonic elasticity detection in the prior art is highly dependent on the operator, has a low discrimination rate sensitive to motion, and uses magnetic resonance elasticity. The scanning time of imaging detection is too long, the price is high, the equipment resources are tight, and the problems of bedside detection and rapid screening cannot be applied

Images