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Application of radix bupleuri, os draconis and oyster soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, radix bupleuri, os draconis and oyster soup variation in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, and self-designed radix bupleuri and radix puerariae lobatae soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease

A technology for hand, foot and mouth disease and Gegen decoction, which can be used in drug delivery, pharmaceutical formulations, antiviral agents, etc., to solve problems such as transmission and missing treatment windows.

Inactive Publication Date: 2020-03-27
JIUJIANG UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] To sum up, in the existing western medicine treatment plan for hand, foot and mouth disease, there is no specific anti-enteroviral drug at present. It is generally recommended to use interferon α spray / atomization or intravenous infusion of ribavirin, and "early use is helpful." Certain curative effect", the effect of medication has great limitations; while the traditional Chinese medicine treatment plan is based on clearing away heat and detoxification as the basic idea, and is mostly used in the stage I rash, but the stage I changes to stage II nerve involvement after only 1-5 days period, a slight delay will miss the treatment window

Method used

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  • Application of radix bupleuri, os draconis and oyster soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, radix bupleuri, os draconis and oyster soup variation in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, and self-designed radix bupleuri and radix puerariae lobatae soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease
  • Application of radix bupleuri, os draconis and oyster soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, radix bupleuri, os draconis and oyster soup variation in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, and self-designed radix bupleuri and radix puerariae lobatae soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease
  • Application of radix bupleuri, os draconis and oyster soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, radix bupleuri, os draconis and oyster soup variation in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease, and self-designed radix bupleuri and radix puerariae lobatae soup in preparing medicine capable of treating adiaphoresis hand-foot-and-mouth disease

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Effect test

Embodiment Construction

[0083] The following clinical data illustrate the effect of traditional Chinese medicine on hand, foot and mouth disease.

[0084] In order to verify the therapeutic effect of the present invention on the anhidrosis patients with hand, foot and mouth disease in stage 1 and stage 2, the research group visited the Department of Traditional Chinese Medicine of Tanghe County Rehabilitation and Youfu Hospital in Nanyang City, Henan Province from March 2017 to December 2018. Inclusion criteria for children with hand, foot and mouth disease were carried out in clinical trials, which are described as follows:

[0085] 1. Diagnostic criteria

[0086] (1) Clinically diagnosed cases

[0087] 1. Incubation period

[0088] Mostly 2-10 days, with an average of 3-5 days.

[0089] 2. Clinical symptoms and signs

[0090] According to the occurrence and development process of the disease, the stages and types of hand, foot and mouth disease are:

[0091] Phase 1 - Rash phase: Mainly manife...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to application of a radix bupleuri, os draconis and oyster soup in preparing a medicine capableof treating a first-phase and second-phase adiaphoresis hand-foot-and-mouth disease, a radix bupleuri, os draconis and oyster soup variation in preparing the medicine capable of treating the first-phase and second-phase adiaphoresis hand-foot-and-mouth disease, and a self-designed radix bupleuri and radix puerariae lobatae soup in preparing the medicine capable of treating the first-phase and second-phase adiaphoresis hand-foot-and-mouth disease. A clinic experiment indicates that the invention has an obvious advantage on the aspects of recovery, effect performing and a number of qualified voters, and a difference is a statistic difference. From specific symptoms, an experimental group has statistical significance for the advantages on three symptom aspects, including a rash distribution situation, appetite loss and dry mouth and lips, and has the advantages but does not have the statistic difference on the aspects of salivation, tired expression, dysphoria, skittishness, vomiting, dysphoria, limb shaking and myasthenia.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to the application of Chaihujia Longgu Muli Decoction and its modification and self-made Chaihu Gegen Decoction in the treatment of stage 1 and stage 2 patients with anhidrosis of hand, foot and mouth disease. Background technique [0002] Hand, foot and mouth disease is an infectious disease caused by enterovirus. It mostly occurs in children under 5 years old. It manifests as mouth pain, anorexia, low-grade fever, small herpes or small ulcers on hands, feet, mouth and other parts. Most children recover by themselves in about a week. , a small number of children can cause myocarditis, pulmonary edema, aseptic meningoencephalitis and other complications. Individual critically ill children develop rapidly and lead to death. [0003] In the "Guidelines for the Diagnosis and Treatment of Hand, Foot and Mouth Disease" issued by the National Health Commission in 20...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P31/14A61K33/26A61K35/02A61K35/618
CPCA61K9/0014A61K9/0095A61K33/26A61K35/02A61K35/618A61K36/076A61K36/233A61K36/344A61K36/539A61K36/54A61K36/708A61K36/714A61K36/725A61K36/8888A61K36/9068A61P31/14A61K2300/00
Inventor 王新锋邓安远涂华新李萌余玛俐樊伊娜彭虎郑长石
Owner JIUJIANG UNIVERSITY
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